Evidence map›Paper›PMID 31263747›Full record

ArticleNPJ breast cancer2019

LobSig is a multigene predictor of outcome in invasive lobular carcinoma.

Amy E McCart Reed, Samir Lal, Jamie R Kutasovic, Leesa Wockner, Alan Robertson, Xavier M de Luca, Priyakshi Kalita-de Croft, Andrew J Dalley, Craig P Coorey, Luyu Kuo and 11 more

Open access · goldAbstract read
In one paragraph

Article in NPJ breast cancer, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 45 citations in OpenAlex.

  1. Review
  2. Toward targeted therapeutics for lobular breast cancer.The Journal of clinical investigation · 2026
    Review
  3. Article
  4. Spatial transcriptomics reveals tumor microenvironment-driven subtypes of invasive lobular carcinoma.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  5. The Canadian Breast Cancer Symposium 2025: Meeting Report.Current oncology (Toronto, Ont.) · 2025
    Article
  6. Article
  7. Pitfalls in the Histological Diagnosis of Morphologic Variants of Invasive Lobular Carcinoma of the Breast.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2025
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Association betweenRadiology and oncology · 2023
    Article
  16. Response to Maltoni, Puccetti, Poli, et al.Journal of the National Cancer Institute · 2023
    Article
  17. Genomic assays for lobular breast carcinoma.Journal of clinical and translational research · 2022
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 2 institutions in 2 countries.

Amy E McCart Reed *1UQ Centre for Clinical Research, Faculty of Medicine, The University of Queensland, Herston, QLD 4029 Australia.ORCID 0000-0001-5387-2791
Samir Lal *1UQ Centre for Clinical Research, Faculty of Medicine, The University of Queensland, Herston, QLD 4029 Australia.
Jamie R Kutasovic1UQ Centre for Clinical Research, Faculty of Medicine, The University of Queensland, Herston, QLD 4029 Australia.ORCID 0000-0001-5410-3636
Leesa Wockner2QIMR Berghofer Medical Research Institute, Herston, Brisbane, QLD 4006 Australia.
Alan Robertson3Institute for Molecular Bioscience, The University of Queensland, St Lucia, Brisbane, QLD 4072 Australia.
Xavier M de Luca1UQ Centre for Clinical Research, Faculty of Medicine, The University of Queensland, Herston, QLD 4029 Australia.ORCID 0000-0002-2564-5126
Priyakshi Kalita-de Croft1UQ Centre for Clinical Research, Faculty of Medicine, The University of Queensland, Herston, QLD 4029 Australia.ORCID 0000-0001-8877-7655
Andrew J Dalley1UQ Centre for Clinical Research, Faculty of Medicine, The University of Queensland, Herston, QLD 4029 Australia.ORCID 0000-0002-8362-6492
Craig P Coorey1UQ Centre for Clinical Research, Faculty of Medicine, The University of Queensland, Herston, QLD 4029 Australia.
Luyu Kuo1UQ Centre for Clinical Research, Faculty of Medicine, The University of Queensland, Herston, QLD 4029 Australia.
Kaltin Ferguson1UQ Centre for Clinical Research, Faculty of Medicine, The University of Queensland, Herston, QLD 4029 Australia.
Colleen Niland1UQ Centre for Clinical Research, Faculty of Medicine, The University of Queensland, Herston, QLD 4029 Australia.
Gregory Miller1UQ Centre for Clinical Research, Faculty of Medicine, The University of Queensland, Herston, QLD 4029 Australia.
Julie Johnson1UQ Centre for Clinical Research, Faculty of Medicine, The University of Queensland, Herston, QLD 4029 Australia.
Lynne E Reid1UQ Centre for Clinical Research, Faculty of Medicine, The University of Queensland, Herston, QLD 4029 Australia.
Renique Males1UQ Centre for Clinical Research, Faculty of Medicine, The University of Queensland, Herston, QLD 4029 Australia.
Jodi M Saunus1UQ Centre for Clinical Research, Faculty of Medicine, The University of Queensland, Herston, QLD 4029 Australia.
Georgia Chenevix-Trench2QIMR Berghofer Medical Research Institute, Herston, Brisbane, QLD 4006 Australia.
Lachlan Coin3Institute for Molecular Bioscience, The University of Queensland, St Lucia, Brisbane, QLD 4072 Australia.
Sunil R Lakhani1UQ Centre for Clinical Research, Faculty of Medicine, The University of Queensland, Herston, QLD 4029 Australia.
Peter T Simpson1UQ Centre for Clinical Research, Faculty of Medicine, The University of Queensland, Herston, QLD 4029 Australia.ORCID 0000-0002-4816-8289
The University of Queensland · AUQIMR Berghofer Medical Research Institute · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Invasive lobular carcinoma (ILC) is the most common special type of breast cancer, and is characterized by functional loss of E-cadherin, resulting in cellular adhesion defects. ILC typically present as estrogen receptor positive, grade 2 breast cancers, with a good short-term prognosis. Several large-scale molecular profiling studies have now dissected the unique genomics of ILC. We have undertaken an integrative analysis of gene expression and DNA copy number to identify novel drivers and prognostic biomarkers, using in-house (

Indexed as

Breast cancerCancer genomics

Identifiers

PMID31263747
PMCPMC6597578
OpenAlexW2953595023

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.