Optimization of a Methodology for Quantification and Removal of Zinc Gives Insights Into the Effect of This Metal on the Stability and Function of the Zinc-Binding Co-chaperone Ydj1.

Jemmyson Romário de Jesus, Annelize Zambon Barbosa Aragão, Marco Aurélio Zezzi Arruda, Carlos H I Ramos

Open access · goldAbstract read

In one paragraph

Article in Frontiers in chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it

0cells of the map it votes in

3citing papers in PubMed

0.5field-weighted citation impact, top 36% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 12 citations in OpenAlex.

Type I Hsp40s/DnaJs aggregates exhibit features reminiscent of amyloidogenic structures.The FEBS journal · 2024
Article
Understanding the relationship between viral infections and trace elements from a metallomics perspective: implications for COVID-19.Metallomics : integrated biometal science · 2020
Review
Zinc finger structure determination by NMR: Why zinc fingers can be a handful.Progress in nuclear magnetic resonance spectroscopy
Review

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Jemmyson Romário de JesusDepartment of Organic Chemistry, Institute of Chemistry, University of Campinas - UNICAMP, Campinas, Brazil.

Annelize Zambon Barbosa AragãoDepartment of Organic Chemistry, Institute of Chemistry, University of Campinas - UNICAMP, Campinas, Brazil.

Marco Aurélio Zezzi ArrudaNational Institute of Science and Technology for Bioanalytics, Institute of Chemistry, University of Campinas - UNICAMP, Campinas, Brazil.

Carlos H I RamosDepartment of Organic Chemistry, Institute of Chemistry, University of Campinas - UNICAMP, Campinas, Brazil.

Universidade Estadual de Campinas (UNICAMP) · BRUniversidade Federal do Rio de Janeiro · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ydj1, a class B J-protein (Hsp40) in yeast, has two zinc finger domains in each monomer and belongs to an important co-chaperone family that plays crucial roles in cells, such as recognizing and binding partially folded proteins and assisting the Hsp70 chaperone family in protein folding. Yeast cells with

Indexed as

homeostasisHsp40ICP-MSprotein folding and stabilityprotein structure/function relationshipzinc

Identifiers

PMID31263692

DOI10.3389/fchem.2019.00416

PMCPMC6584821

OpenAlexW2949600504

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.