Evidence map›Paper›PMID 31263584›Full record

ArticleBMJ global health2019

Does voluntary medical male circumcision protect against sexually transmitted infections among men and women in real-world scale-up settings? Findings of a household survey in KwaZulu-Natal, South Africa.

Stephanie Davis, Carlos Toledo, Lara Lewis, Brendan Maughan-Brown, Kassahun Ayalew, Ayesha B M Kharsany

Open access · goldAbstract read
In one paragraph

Article in BMJ global health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Article
  3. Observational
  4. Article
  5. Men undergoing medical circumcision at a community health centre: Knowledge and attitudes.South African family practice : official journal of the South African Academy of Family Practice/Primary Care · 2025
    Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Large age shifts in HIV-1 incidence patterns in KwaZulu-Natal, South Africa.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  13. Current critiques of the WHO policy on female genital mutilation.International journal of impotence research · 2021
    Review
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 3 countries.

Stephanie Davis *Division of Global HIV and Tuberculosis, US Centers for Disease Control and Prevention, Atlanta, Georgia, USA.ORCID 0000-0003-4878-9701
Carlos Toledo *Division of Global HIV and Tuberculosis, US Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Lara LewisNelson R. Mandela School of Medicine, Centre for the AIDS Programme of Research in South Africa, Durban, South Africa.
Brendan Maughan-BrownSouthern Africa Labour and Development Research Unit, University of Cape Town, Cape Town, South Africa.
Kassahun AyalewDivision of Global HIV and Tuberculosis, US Centers for Disease Control and Prevention, Durban, South Africa.
Ayesha B M KharsanyNelson R. Mandela School of Medicine, Centre for the AIDS Programme of Research in South Africa, Durban, South Africa.
Centers for Disease Control and Prevention · USCentre for the AIDS Programme of Research in South Africa · ZACenters for Disease Control and Prevention · UGUniversity of Cape Town · ZA

Funding

Identifying sources of HIV infection in adolescent girls in rural South AfricaR01HD083343 · NICHD · CENTRE/AIDS PROGRAMME/RES/SOUTH AFRICA · PI KHARSANY, AYESHA BM, KOHLER, HANS-PETER · 2015 to 2019
$1.7M
CGH CDC HHS U2G GH000372NICHD NIH HHS R01 HD083343
6 · The paper itself

Abstract

introductionMale circumcision (MC) confers partial protection to men against HIV and, in research settings, some sexually transmitted infections (STIs). It is also associated with protection from some STIs among female partners. However, real-world data on changes in STI transmission associated with large-scale public African medical male circumcision (MMC) conducted for HIV prevention are lacking and would improve estimates of the health impact of MMC.

methodsThe HIV Incidence Provincial Surveillance System is a community-based surveillance platform for HIV prevalence, incidence and intervention coverage trends in KwaZulu-Natal province, South Africa. HIPPS collected cross-sectional self-reported data on circumcision status (from men), partner circumcision status for past three partners (from women) and demographic characteristics and behavioural risk factors; and tested participants for HIV, herpes simplex virus type 2 (HSV-2), syphilis, hepatitis B,

resultsAmong men, MMC had a protective association with HSV-2 (OR 0.66, 95% CI 0.50 to 0.86), hepatitis B (OR 0.53, 95% CI 0.30 to 0.95), HIV (OR 0.50, 95% CI 0.38 to 0.65) and

conclusionThese real-world data, supporting protective associations between MMC conducted for HIV prevention and STIs in men and women, can help clarify the full impact of MMC and support a role in broader sexual health programming.

Indexed as

community-based surveycross-sectional surveyHIVprevention strategies

Identifiers

PMID31263584
PMCPMC6570991
OpenAlexW2947336588

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.