Evidence map›Paper›PMID 31263568›Full record

ReviewNPJ biofilms and microbiomes

Selective pressures during chronic infection drive microbial competition and cooperation.

Jiwasmika Baishya, Catherine A Wakeman

Abstract readReview
In one paragraph

Review in NPJ biofilms and microbiomes. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed.

  1. Oxidative stress inducesMicrobiology spectrum · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Metabolic cross-talk promotes persistence ofbioRxiv : the preprint server for biology · 2025
    Article
  13. Antibiotics (Basel, Switzerland) · 2025
    Article
  14. Review
  15. Article
  16. Exploring the Genetic and Functional Diversity ofInternational journal of molecular sciences · 2025
    Article
  17. Article
  18. Article
  19. Article
  20. Antibiotics (Basel, Switzerland) · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jiwasmika BaishyaDepartment of Biological Sciences, Texas Tech University, Lubbock, TX USA.ORCID 0000-0003-0205-4777
Catherine A WakemanDepartment of Biological Sciences, Texas Tech University, Lubbock, TX USA.ORCID 0000-0003-0311-6669

Funding

Physiological profiling of Pseudomonas aeruginosa biofilm subpopulationsR15GM128072 · NIGMS · TEXAS TECH UNIVERSITY · PI WAKEMAN, CATHERINE ANN · 2018 to 2018
$432k
NIGMS NIH HHS R15 GM128072
6 · The paper itself

Abstract

Chronic infections often contain complex mixtures of pathogenic and commensal microorganisms ranging from aerobic and anaerobic bacteria to fungi and viruses. The microbial communities present in infected tissues are not passively co-existing but rather actively interacting with each other via a spectrum of competitive and/or cooperative mechanisms. Competition versus cooperation in these microbial interactions can be driven by both the composition of the microbial community as well as the presence of host defense strategies. These interactions are typically mediated via the production of secreted molecules. In this review, we will explore the possibility that microorganisms competing for nutrients at the host-pathogen interface can evolve seemingly cooperative mechanisms by controlling the production of subsets of secreted virulence factors. We will also address interspecies versus intraspecies utilization of community resources and discuss the impact that this phenomenon might have on co-evolution at the host-pathogen interface.

Indexed as

Microbial InteractionsMicrobiotaSelection, GeneticCoinfectionHost-Pathogen InteractionsHumansEvolutionMicrobiomePathogens

Identifiers

PMID31263568
PMCPMC6555799

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.