Evidence map›Paper›PMID 31263410›Full record

ReviewFrontiers in pharmacology2019

Medicinal Plants and Natural Products Used in Cataract Management.

Devesh Tewari, Ovidiu Samoilă, Diana Gocan, Andrei Mocan, Cadmiel Moldovan, Hari Prasad Devkota, Atanas G Atanasov, Gokhan Zengin, Javier Echeverría, Dan Vodnar and 2 more

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in pharmacology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
9.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it, 71 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Lebanese Medicinal Plants with Ophthalmic Properties.Pharmaceuticals (Basel, Switzerland) · 2025
    Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Neoteric Role of Quercetin in Visual Disorders.Current drug research reviews · 2024
    Review
  10. Frontiers in chemistry · 2024
    Article
  11. Article
  12. Review
  13. Medicinal Plants Used for Eye Conditions in Mexico-A Review.Pharmaceuticals (Basel, Switzerland) · 2023
    Review
  14. Review
  15. Review
  16. Article
  17. Article
  18. Review
  19. Anticataract Effect of the Aqueous Extract of the Flowers ofAdvances in pharmacological and pharmaceutical sciences · 2023
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 7 countries.

Devesh TewariDepartment of Pharmacognosy, School of Pharmaceutical Sciences, Lovely Professional University, Phagwara, India.
Ovidiu SamoilăDepartment of Ophthalmology, Iuliu Haţieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
Diana GocanDepartment of Ophthalmology, Iuliu Haţieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
Andrei MocanDepartment of Pharmaceutical Botany, Iuliu Haţieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
Cadmiel MoldovanDepartment of Pharmaceutical Botany, Iuliu Haţieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
Hari Prasad DevkotaGraduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan.
Atanas G AtanasovInstitute of Genetics and Animal Breeding, Polish Academy of Sciences, Jastrzębiec, Poland.
Gokhan ZenginDepartment of Biology, Faculty of Science, Selcuk University, Konya, Turkey.
Javier EcheverríaDepartamento de Ciencias del Ambiente, Facultad de Química y Biología, Universidad de Santiago de Chile, Santiago, Chile.
Dan VodnarDepartment of Food Science, University of Agricultural Sciences and Veterinary Medicine of Cluj-Napoca, Cluj-Napoca, Romania.
Bianca SzaboDepartment of Anatomy, Iuliu Haţieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
Gianina CrişanDepartment of Pharmaceutical Botany, Iuliu Haţieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
Iuliu Hațieganu University of Medicine and Pharmacy · ROKumamoto University · JPLovely Professional University · INSelçuk University · TRUniversidad de Santiago de Chile · CLUniversity of Agricultural Sciences and Veterinary Medicine of Cluj-Napoca · ROUniversity of Vienna · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cataract is the leading reason of blindness worldwide and is defined by the presence of any lens opacities or loss of transparency. The most common symptoms of cataract are impaired vision, decreased contrast sensitivity, color disturbance, and glare. Oxidative stress is among the main mechanisms involved in the development of age-related cataract. Surgery through phacoemulsification and intraocular lens implantation is the most effective method for cataract treatment, however, there are chances of serious complications and irreversible loss of vision associated with the surgery. Natural compounds consisting of antioxidant or anti-inflammatory secondary metabolites can serve as potential leads for anticataract agents. In this review, we tried to document medicinal plants and plant-based natural products used for cataract treatment worldwide, which are gathered from available ethnopharmacological/ethnobotanical data. We have extensively explored a number of recognized databases like Scifinder, PubMed, Science Direct, Google Scholar, and Scopus by using keywords and phrases such as "cataract", "blindness", "traditional medicine", "ethnopharmacology", "ethnobotany", "herbs", "medicinal plants", or other relevant terms, and summarized the plants/phytoconstituents that are evaluated in different models of cataract and also tabulated 44 plants that are traditionally used in cataract in various folklore medical practices. Moreover, we also categorized the plants according to scientific studies carried out in different cataract models with their mechanisms of action.

Indexed as

aldose reductaseantioxidantcataractlens opacityMAPKmedicinal plantsnatural products

Identifiers

PMID31263410
PMCPMC6585469
OpenAlexW2951580934

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.