ReviewFrontiers in cellular neuroscience2019
Hippocampal Sequences During Exploration: Mechanisms and Functions.
Review in Frontiers in cellular neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
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Who cites it
35 citing papers in PubMed.
- Article
- Medial entorhinal-hippocampal desynchronization parallels the emergence of memory impairment in a mouse model of Alzheimer's disease pathology.Cell reports · 2026Article
- Deciphering hippocampal place codes in weak theta rhythms.Nature communications · 2026Article
- Dynamical modulation of hippocampal replay through firing rate adaptation.Nature communications · 2026Article
- Emotional shaping of spatial encoding along the dorsal ventral axis of the hippocampus.Frontiers in systems neuroscience · 2026Review
- Theta-nested gamma oscillations balance prediction and vigilance in spatial navigation.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Article
- A scalable reinforcement learning framework inspired by hippocampal memory mechanisms for efficient contextual and sequential decision making.Scientific reports · 2025Article
- Direct entorhinal control of CA1 temporal coding.Nature communications · 2025Article
- Selective inhibition in CA3: A mechanism for stable pattern completion through heterosynaptic plasticity.PLoS computational biology · 2025Article
- Review
- Timing is everything: The effect of early-life seizures on developing neuronal circuits subserving spatial memory.Epilepsia open · 2025Review
- [Synchronized neural rhythms in rat hippocampal CA1 region and orbitofrontal cortex are involved in learning and memory consolidation in spatial goal-directed tasks].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2025Article
- The generation of a neuronal phase code for space.Clinical and translational medicine · 2024Article
- Integration of rate and phase codes by hippocampal cell-assemblies supports flexible encoding of spatiotemporal context.Nature communications · 2024Article
- The mosaic structure of the mammalian cognitive map.Learning & behavior · 2024Review
- Offline memory replay in recurrent neuronal networks emerges from constraints on online dynamics.The Journal of physiology · 2023Article
- Learning to predict future locations with internally generated theta sequences.PLoS computational biology · 2023Article
- The cerebellum promotes sequential foraging strategies and contributes to the directional modulation of hippocampal place cells.iScience · 2023Article
- Inhibitory hippocampus-medial septum projection controls locomotion and exploratory behavior.Frontiers in synaptic neuroscience · 2023Article
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2 authors.
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Abstract
Although the hippocampus plays a critical role in spatial and episodic memories, the mechanisms underlying memory formation, stabilization, and recall for adaptive behavior remain relatively unknown. During exploration, within single cycles of the ongoing theta rhythm that dominates hippocampal local field potentials, place cells form precisely ordered sequences of activity. These neural sequences result from the integration of both external inputs conveying sensory-motor information, and intrinsic network dynamics possibly related to memory processes. Their endogenous replay during subsequent sleep is critical for memory consolidation. The present review discusses possible mechanisms and functions of hippocampal theta sequences during exploration. We present several lines of evidence suggesting that these neural sequences play a key role in information processing and support the formation of initial memory traces, and discuss potential functional distinctions between neural sequences emerging during theta vs. awake sharp-wave ripples.
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