ArticleIndian journal of anaesthesia2019
Continuous wound infiltration of bupivacaine at two different anatomical planes for caesarean analgesia - A randomised clinical trial.
Article in Indian journal of anaesthesia, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
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Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.
- PROSPECT guideline for elective caesarean section: updated systematic review and procedure-specific postoperative pain management recommendations.Anaesthesia · 2021Guideline
- Wound infiltration with local anesthetics during cesarean delivery with intrathecal opioids: A systematic review and meta-analysis of randomized control trials.Pregnancy (Hoboken, N.J.) · 2026Article
- Assessment of the Safety and Efficiency of a Preperitoneal Continuous Infusion Using Bupivacaine after Abdominal Laparotomy in Digestive Carcinology.Anesthesiology research and practice · 2023Article
- Ropivacaine instillation through subgaleal drain: A novel approach for acute post-craniotomy pain.Indian journal of anaesthesia · 2022Article
- Ultrasound-guided transversalis fascia plane block versus wound infiltration for both acute and chronic post-caesarean pain management - A randomised controlled trial.Indian journal of anaesthesia · 2022Article
- Continuous wound infiltration of local anaesthetics for acute postoperative pain - A revisit.Indian journal of anaesthesia · 2019Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
aimsContinuous wound infiltration of local anaesthetics provide postoperative analgesia by peripheral nociceptors blockade.The placement of wound infiltration catheter in the optimal anatomical plane of surgical wound may play a significant role in reducing postoperative pain depends on the surgical procedure. We hypothesised that preperitoneal infusion of local anaesthetics will reduce the postoperative opioid consumption as compared to subcutaneous infusion following cesarean section.
methodsThis was a randomised, double-blinded clinical trial. Fifty-two pregnant women who underwent lower segment caesarean section by Pfannensteil incision, under spinal anaesthesia, were randomised to group 'subcutaneous' and group 'preperitoneal'. A wound infiltration catheter was placed in the subcutaneous or preperitoneal plane, depending on their randomisation at the end of the surgery. Bupivacaine of 0.25% at 5 mL/h was infused for the next 48 h. Pain was assessed using numerical rating scale at 1, 2, 3, 4, 5, 6, 12, 24, 36 and 48 h after surgery. Cumulative postoperative consumption and adverse effects of morphine and complications of the procedure were looked for.
resultsCumulative 48-h morphine consumption showed no statistical significance between the preperitoneal group (15.96 ± 7.69 mg) and subcutaneous group (21.26 ± 11.03 mg);
conclusionPostoperative cumulative morphine consumption and pain scores are comparable when bupivacaine is infused continuously through wound infiltration catheter either in the preperitoneal or subcutaneous layer following Caesarean delivery.
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