ArticleJournal of perinatology : official journal of the California Perinatal Association2020
Frequency-following response among neonates with progressive moderate hyperbilirubinemia.
Article in Journal of perinatology : official journal of the California Perinatal Association, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed, 13 citations in OpenAlex.
- The frequency-following response in late preterm neonates: a pilot study.Frontiers in psychology · 2024Article
- Implementation of Machine Learning on Human Frequency-Following Responses: A Tutorial.Seminars in hearing · 2022Review
- Neonatal Frequency-Following Responses: A Methodological Framework for Clinical Applications.Seminars in hearing · 2022Review
- Neuroaudiological Considerations for the Auditory Brainstem Response and Middle Latency Response Revisited: Back to the Future.Seminars in hearing · 2022Review
- TcB, FFR, phototherapy and the persistent occurrence of kernicterus spectrum disorder.Journal of perinatology : official journal of the California Perinatal Association · 2020Article
- Analyzing the FFR: A tutorial for decoding the richness of auditory function.Hearing research · 2019Review
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo evaluate the feasibility of auditory monitoring of neurophysiological status using frequency-following response (FFR) in neonates with progressive moderate hyperbilirubinemia, measured by transcutaneous (TcB) levels. STUDY
designABR and FFR measures were compared and correlated with TcB levels across three groups. Group I was a healthy cohort (n = 13). Group II (n = 28) consisted of neonates with progressive, moderate hyperbilirubinemia and Group III consisted of the same neonates, post physician-ordered phototherapy.
resultFFR amplitudes in Group I controls (TcB = 83.1 ± 32.5µmol/L; 4.9 ± 1.9 mg/dL) were greater than Group II (TcB = 209.3 ± 48.0µmol/L; 12.1 ± 2.8 mg/dL). After TcB was lowered by phototherapy, FFR amplitudes in Group III were similar to controls. Lower TcB levels correlated with larger FFR amplitudes (r = -0.291, p = 0.015), but not with ABR wave amplitude or latencies.
conclusionThe FFR is a promising measure of the dynamic neurophysiological status in neonates, and may be useful in tracking neurotoxicity in infants with hyperbilirubinemia.
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Registered trials
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