Evidence map›Paper›PMID 31262838›Full record

ArticleJournal of bacteriology2019

Polar Effects of Transposon Insertion into a Minimal Bacterial Genome.

Clyde A Hutchison, Chuck Merryman, Lijie Sun, Nacyra Assad-Garcia, R Alexander Richter, Hamilton O Smith, John I Glass

Abstract read
In one paragraph

Article in Journal of bacteriology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Article
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  5. EngineeringMetabolic engineering communications · 2025
    Article
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  7. Review
  8. Article
  9. Article
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  17. The reliance of glycerol utilization by Cupriavidus necator on COApplied microbiology and biotechnology · 2022
    Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Clyde A HutchisonSynthetic Biology Group, J. Craig Venter Institute, La Jolla, California, USA chutchis@jcvi.org.
Chuck MerrymanSynthetic Biology Group, J. Craig Venter Institute, La Jolla, California, USA.
Lijie SunSynthetic Biology Group, J. Craig Venter Institute, La Jolla, California, USA.
Nacyra Assad-GarciaSynthetic Biology Group, J. Craig Venter Institute, Rockville, Maryland, USA.
R Alexander RichterSynthetic Biology Group, J. Craig Venter Institute, La Jolla, California, USA.
Hamilton O SmithSynthetic Biology Group, J. Craig Venter Institute, La Jolla, California, USA.
John I GlassSynthetic Biology Group, J. Craig Venter Institute, La Jolla, California, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Global transposon mutagenesis is a valuable tool for identifying genes required for cell viability. Here we present a global analysis of the orientation of viable Tn

Indexed as

BacteriaBacterial ProteinsDNA Transposable ElementsGenome, BacterialMutagenesis, InsertionalTranscription, GeneticBacterial ProteinsDNA Transposable Elementsminimal cellpolaritytransposon mutagenesis

Identifiers

PMID31262838
PMCPMC6755753

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.