Evidence map›Paper›PMID 31262533›Full record

ReviewTrends in microbiology2019

Molecular Mechanism of HIV-1 Entry.

Bing Chen

Abstract readReview
In one paragraph

Review in Trends in microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 208 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
208citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

208 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
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  6. Review
  7. Article
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  16. Review
  17. Review
  18. Article
  19. Searching for a HIV-1 Cure.Theranostics · 2026
    Review
  20. Review

148 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Bing ChenDivision of Molecular Medicine, Boston Children's Hospital, and Department of Pediatrics, Harvard Medical School, 3 Blackfan Street, Boston, MA 02115, USA. Electronic address: bchen@crystal.harvard.edu.

Funding

Virus biology scientific research support componentUM1AI100645 · NIAID · DUKE UNIVERSITY · PI MCMICHAEL, ANDREW JAMES · 2012 to 2018
$204.7M
Structure-function studies of the membrane-interacting domains of HIV-1 Env spikeR01AI127193 · NIAID · BOSTON CHILDREN'S HOSPITAL · PI CHEN, BING, HARRISON, STEPHEN COPLAN · 2016 to 2025
$8.4M
Structural Basis of Coreceptor Recognition by HIV-1 Envelope SpikeR01AI141002 · NIAID · BOSTON CHILDREN'S HOSPITAL · PI CHEN, BING · 2018 to 2022
$2.6M
Crystallographic studies of intact and fully glycosylated HIV-1 gp120R01AI106488 · NIAID · BOSTON CHILDREN'S HOSPITAL · PI CHEN, BING · 2013 to 2017
$2.2M
Novel therapeutics targeting the membrane proximal external region of HIV-1 EnvR56AI129721 · NIAID · BOSTON CHILDREN'S HOSPITAL · PI CHEN, BING · 2017 to 2017
$674k
NIAID NIH HHS R01 AI106488NIAID NIH HHS R01 AI127193NIAID NIH HHS R01 AI141002NIAID NIH HHS R56 AI129721NIAID NIH HHS UM1 AI100645
6 · The paper itself

Abstract

HIV-1 envelope glycoprotein [Env; trimeric (gp160)

Indexed as

Virus InternalizationCD4 AntigensHIV-1HIV Envelope Protein gp160HIV InfectionsLife Cycle StagesMembrane FusionModels, MolecularProtein Interaction Domains and MotifsReceptors, CCR5Receptors, CXCR4CCR5 protein, humanCD4 AntigensCXCR4 protein, humanHIV Envelope Protein gp160Receptors, CCR5Receptors, CXCR4envelope glycoproteinHIV-1membrane fusionviral entry

Identifiers

PMID31262533
PMCPMC6744290

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.