Evidence map›Paper›PMID 31262209›Full record

ArticleChannels (Austin, Tex.)2019

Peter R Strege, Arnaldo Mercado-Perez, Amelia Mazzone, Yuri A Saito, Cheryl E Bernard, Gianrico Farrugia, Arthur Beyder

Open access · goldAbstract read
In one paragraph

Article in Channels (Austin, Tex.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. A Novel Function of NaFASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Article
  4. Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023
    Review
  5. Article
  6. Article
  7. Review
  8. Capsaicin as an amphipathic modulator of NaChannels (Austin, Tex.) · 2022
    Article
  9. Review
  10. Mechanotransduction in gastrointestinal smooth muscle cells: role of mechanosensitive ion channels.American journal of physiology. Gastrointestinal and liver physiology · 2021
    Review
  11. Article
  12. Expression of the regulated isoform of the electrogenic NaAmerican journal of physiology. Gastrointestinal and liver physiology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Peter R Stregea Enteric NeuroScience Program, Division of Gastroenterology and Hepatology, Mayo Clinic , Rochester , MN , USA.
Arnaldo Mercado-Pereza Enteric NeuroScience Program, Division of Gastroenterology and Hepatology, Mayo Clinic , Rochester , MN , USA.
Amelia Mazzonea Enteric NeuroScience Program, Division of Gastroenterology and Hepatology, Mayo Clinic , Rochester , MN , USA.
Yuri A Saitoa Enteric NeuroScience Program, Division of Gastroenterology and Hepatology, Mayo Clinic , Rochester , MN , USA.
Cheryl E Bernarda Enteric NeuroScience Program, Division of Gastroenterology and Hepatology, Mayo Clinic , Rochester , MN , USA.
Gianrico Farrugiaa Enteric NeuroScience Program, Division of Gastroenterology and Hepatology, Mayo Clinic , Rochester , MN , USA.
Arthur Beydera Enteric NeuroScience Program, Division of Gastroenterology and Hepatology, Mayo Clinic , Rochester , MN , USA.
Mayo Clinic in Arizona · USMayo Clinic in Florida · US

Funding

PILOT AND FEASIBILTY PROGRAMP30DK084567 · NIDDK · MAYO CLINIC ROCHESTER · PI GREGORY J. GORES · 2009 to 2026
$22.2M
MECHANOTRANSDUCTION IN INTESTINAL SMOOTH MUSCLE CELLSR01DK052766 · NIDDK · MAYO CLINIC ROCHESTER · PI BEYDER, ARTHUR, FARRUGIA, GIANRICO · 1997 to 2025
$8.3M
Mechanisms of mechanotransduction in the enterochromaffin cellsK08DK106456 · NIDDK · MAYO CLINIC ROCHESTER · PI BEYDER, ARTHUR · 2015 to 2019
$813k
Genetic epidemiology of irritable bowel syndrome (IBS)K23DK066271 · NIDDK · MAYO CLINIC ROCHESTER · PI SAITO LOFTUS, YURI ANN · 2004 to 2008
$630k
Enterochromaffin cell mechanotransduction and mechanosensitive serotonin release depend on calcium signaling downstream of Piezo2 activationR03DK119683 · NIDDK · MAYO CLINIC ROCHESTER · PI BEYDER, ARTHUR · 2019 to 2020
$159k
NIDDK NIH HHS K08 DK106456NIDDK NIH HHS K23 DK066271NIDDK NIH HHS P30 DK084567NIDDK NIH HHS R01 DK052766NIDDK NIH HHS R03 DK119683
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Mutation, MissenseHEK293 CellsHumansIon Channel GatingMechanotransduction, CellularMyocytes, Smooth MuscleNAV1.5 Voltage-Gated Sodium ChannelShear StrengthSodiumNAV1.5 Voltage-Gated Sodium ChannelSCN5A protein, humanSodiumElectrophysiologyfunctional gastrointestinal disorderion channelirritable bowel syndromemechanotransductionvoltage-gated sodium channel type 5

Identifiers

PMID31262209
PMCPMC6629189
OpenAlexW2955177047

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.