Evidence map›Paper›PMID 31262187›Full record

ArticleEuropean journal of cardiovascular nursing2019

Diagnostic accuracy of office blood pressure compared to home blood pressure in patients with mild cognitive impairment and dementia.

Rianne Aa de Heus, Maxime V Tumelaire, Marcel Gm Olde Rikkert, Jurgen Ahr Claassen

Abstract readComparative Study
In one paragraph

Article in European journal of cardiovascular nursing, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
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3citing papers in PubMed, 1 pooled it
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Rianne Aa de HeusDepartment of Geriatric Medicine, Radboud University Medical Center, The Netherlands.
Maxime V TumelaireDepartment of Geriatric Medicine, Radboud University Medical Center, The Netherlands.
Marcel Gm Olde RikkertDepartment of Geriatric Medicine, Radboud University Medical Center, The Netherlands.
Jurgen Ahr ClaassenDepartment of Geriatric Medicine, Radboud University Medical Center, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHypertension and cognitive impairment often coexist in older people. Office blood pressure measurement is a poor indicator for diagnosing hypertension in the general population. However, its diagnostic accuracy has not been substantially studied in patients with cognitive impairment.

aimThe aim of this study was to determine the proportion of misdiagnosis of hypertension in patients with mild cognitive impairment and dementia compared to no cognitive impairment, by comparing office blood pressure measurement with home blood pressure measurement.

methodsA cross-sectional study including consecutive patients visiting a memory clinic between 2014 and 2017. Home blood pressure was measured for one week according to the European guidelines. Office blood pressure was assessed during routine clinical practice. Using guideline definitions for normal blood pressure and hypertension, we investigated the proportion of disagreement between office blood pressure measurement and home blood pressure measurement. Univariable and multivariable logistic regression compared disagreement in diagnosis between patients with dementia, mild cognitive impairment and no cognitive impairment.

resultsOf 213 patients (aged 73.4±9.0 years, 42% women) 82 had dementia, 65 had mild cognitive impairment and 66 had no cognitive impairment. Mean office blood pressure was 156/84±23/11 mmHg and mean home blood pressure was 139/79±16/10 mmHg. In 31% of patients, there was disagreement in hypertension diagnosis. This proportion was higher for mild cognitive impairment (38.5%) and dementia (35.4%) compared to no cognitive impairment (18.2%), with adjusted odds ratios of 3.7 (95% confidence interval 1.5-9.0),

conclusionsIn memory clinic patients with dementia and mild cognitive impairment, the diagnostic accuracy of office blood pressure measurement is lower compared to patients without cognitive impairment. To avoid the risk of making improper treatment decisions in this vulnerable group, a diagnosis of hypertension should be based on home blood pressure measurement, not office blood pressure measurement.

Indexed as

Data AccuracyAgedAged, 80 and overBlood Pressure DeterminationBlood Pressure MonitorsCognitive DysfunctionCross-Sectional StudiesDementiaFemaleHome Care ServicesHumansHypertensionLogistic ModelsMaleMiddle Agedblood pressureDementiahypertensionmild cognitive impairment

Identifiers

PMID31262187
PMCPMC6764005

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.