Evidence map›Paper›PMID 31261857›Full record

ArticleInternational journal of molecular sciences2019

Cystathionine-Gamma-Lyase-Derived Hydrogen Sulfide-Regulated Substance P Modulates Liver Sieve Fenestrations in Caecal Ligation and Puncture-Induced Sepsis.

Ravinder R Gaddam, Stephen Chambers, Robin Fraser, Victoria C Cogger, David G Le Couteur, Isao Ishii, Madhav Bhatia

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.1field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Inflammation and Organ Injury the Role of Substance P and Its Receptors.International journal of molecular sciences · 2023
    Review
  9. Hydrogen Sulfide and Substance P Levels in Patients withInternational journal of molecular sciences · 2022
    Article
  10. Gases in Sepsis: Novel Mediators and Therapeutic Targets.International journal of molecular sciences · 2022
    Review
  11. Review
  12. Hydrogen Sulfide and the Immune System.Advances in experimental medicine and biology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Ravinder R GaddamDepartment of Pathology and Biomedical Science, University of Otago, Christchurch 8140, New Zealand.
Stephen ChambersDepartment of Pathology and Biomedical Science, University of Otago, Christchurch 8140, New Zealand.
Robin FraserDepartment of Pathology and Biomedical Science, University of Otago, Christchurch 8140, New Zealand.
Victoria C CoggerAgeing and Alzheimers Institute, ANZAC Research Institute, University of Sydney and Concord Hospital, Sydney 2139, Australia.
David G Le CouteurAgeing and Alzheimers Institute, ANZAC Research Institute, University of Sydney and Concord Hospital, Sydney 2139, Australia.
Isao IshiiShowa Pharmaceutical University, Machida 194-8543, Japan.ORCID 0000-0002-5367-205X
Madhav BhatiaDepartment of Pathology and Biomedical Science, University of Otago, Christchurch 8140, New Zealand. madhav.bhatia@otago.ac.nz.
University of Otago · NZThe University of Sydney · AUShowa Pharmaceutical University · JP

Funding

ANZAC Research Institute -Canterbury Medical Research Foundation 13/4University of Otago -
6 · The paper itself

Abstract

Cystathionine-γ-lyase (CSE) isa hydrogen sulfide (H

Indexed as

AnimalsCystathionine gamma-LyaseEndothelial CellsLiverLungMaleMiceMice, Inbred BALB CMice, Inbred C57BLReceptors, Neurokinin-1SepsisSubstance PSulfitesCystathionine gamma-Lyasehydrogen sulfiteReceptors, Neurokinin-1Substance PSulfitescystathionine-gamma-lyasehydrogen sulfideliver sieveneurokinin-1 receptorsubstance P

Identifiers

PMID31261857
PMCPMC6651477
OpenAlexW2953951491

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.