Evidence map›Paper›PMID 31261818›Full record

ArticleBiomolecules2019

Halogen-Substituted Derivatives of

Kyoko Totsuka, Yuka Makioka, Kyoichi Iizumi, Katsunori Takahashi, Yoshiteru Oshima, Haruhisa Kikuchi, Yuzuru Kubohara

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Pharmacological Evidence ThatMolecules (Basel, Switzerland) · 2023
    Article
  4. Review
  5. Juntendo Iji zasshi = Juntendo medical journal · 2023
    Article
  6. International journal of molecular sciences · 2021
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Kyoko TotsukaLaboratory of Health and Life Science, Graduate School of Health and Sports Science, Juntendo University, Inzai, Chiba 270-1695, Japan. k.totsuka0511@gmail.com.
Yuka MakiokaLaboratory of Health and Life Science, Graduate School of Health and Sports Science, Juntendo University, Inzai, Chiba 270-1695, Japan. dmcyx763@yahoo.co.jp.
Kyoichi IizumiLaboratory of Health and Life Science, Department of Health Science, Faculty of Health and Sports Science, Juntendo University, Inzai, Chiba 270-1695, Japan. iizumi@juntendo.ac.jp.
Katsunori TakahashiDepartment of Medical Technology, Faculty of Health Science, Gunma Paz College, Takasaki 370-0006, Japan. k-takahashi@paz.ac.jp.
Yoshiteru OshimaLaboratory of Natural Product Chemistry, Graduate School of Pharmaceutical Sciences, Tohoku University, Aoba-ku, Sendai 980-8578, Japan. oshima@mail.pharm.tohoku.ac.jp.
Haruhisa KikuchiLaboratory of Natural Product Chemistry, Graduate School of Pharmaceutical Sciences, Tohoku University, Aoba-ku, Sendai 980-8578, Japan. hal@mail.pharm.tohoku.ac.jp.
Yuzuru KuboharaLaboratory of Health and Life Science, Graduate School of Health and Sports Science, Juntendo University, Inzai, Chiba 270-1695, Japan. ykuboha@juntendo.ac.jp.
Juntendo University · JPTohoku University · JPGumma Paz College · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Triple-negative breast cancer (TNBC) is highly proliferative and metastatic, and because it lacks three major molecular targets for chemotherapy (estrogen receptor, progesterone receptor, and human epidermal receptor 2), it is extremely refractory. Differentiation-inducing factor 1 (DIF-1) and DIF-3, which are chlorinated alkylphenones, are lead anticancer compounds found in the cellular slime mold

Indexed as

Breast NeoplasmsCell Line, TumorCell MovementCell ProliferationDictyosteliumDose-Response Relationship, DrugFemaleHalogensHexanonesHumansHydrocarbons, ChlorinatedStructure-Activity RelationshipTriple Negative Breast NeoplasmsDifferentiation-inducing factor-1, DictyosteliumHalogensHexanonesHydrocarbons, ChlorinatedAnticancer drugCell migrationDictyostelium discoideumDIF.MetastasisTriple-negative breast cancer

Identifiers

PMID31261818
PMCPMC6681295
OpenAlexW2954469249

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.