Evidence map›Paper›PMID 31261796›Full record

ArticleJournal of clinical medicine2019

Combined Intervention of Physical Activity, Aerobic Exercise, and Cognitive Exercise Intervention to Prevent Cognitive Decline for Patients with Mild Cognitive Impairment: A Randomized Controlled Clinical Study.

Hyuntae Park, Jong Hwan Park, Hae Ri Na, Shimada Hiroyuki, Gwon Min Kim, Min Ki Jung, Woo Kyung Kim, Kyung Won Park

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
60citing papers in PubMed, 10 pooled it
7.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

60 citing papers in PubMed, 10 syntheses or guidelines pooled it, 114 citations in OpenAlex.

  1. Pooled it
  2. A Meta-Analysis of Fall Risk in Older Adults With Alzheimer's Disease.Journal of the American Medical Directors Association · 2024
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  20. Optimal type and dose of exercise to improve cognitive function in healthy and pre-sarcopenic older adults: a bayesian network meta-analysis of randomized controlled trials.European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Hyuntae ParkDepartment of Health Care Science, Dong-A University, Busan 49315, Korea.
Jong Hwan ParkHealth Convergence Medicine Research Group, Biomedical Research Institute, Pusan National University Hospital, Busan 49241, Korea.
Hae Ri NaDepartment of Neurology, Seongnam Center of Senior Health and Bobath Memorial Hospital, Gyeonggi-do 13552, Korea.
Shimada HiroyukiCenter for Gerontology and Social Science, National Center for Geriatrics and Gerontology,Obu 474-8511, Japan.
Gwon Min KimDepartment of Health Care Science, Dong-A University, Busan 49315, Korea.
Min Ki JungDepartment of Health Care Science, Dong-A University, Busan 49315, Korea.
Woo Kyung KimBusan Metropolitan Dementia Center, Busan 49201, Korea.
Kyung Won ParkBusan Metropolitan Dementia Center, Busan 49201, Korea.
Dong-A University · KRNational Center for Geriatrics and Gerontology · JPThe Busan Metropolitan Simin Municipal Library · KRBobath memorial hospital · KRPusan National University Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to investigate the association between a dual-task intervention program and cognitive and physical functions. In a randomized controlled trial, we enrolled 49 individuals with MCI. The MCI diagnosis was based on medical evaluations through a clinical interview conducted by a dementia specialist. Cognitive assessments were performed by neuropsychologists according to standardized methods, including the MMSE and modified Alzheimer's disease Assessment Scale-Cognitive Subscale (ADAS-Cog), both at baseline and at 3 months follow-up. The program comprised physical activity and behavior modification, aerobic exercise, and a cognitive and exercise combined intervention program. Analysis of the subjects for group-time interactions revealed that the exercise group exhibited a significantly improved ADAS-Cog, working memory, and executive function. Total physical activity levels were associated with improvements in working memory function and the modified ADAS-Cog score, and the associations were stronger for daily moderate intensity activity than for daily step count. The 24-week combined intervention improved cognitive function and physical function in patients with MCI relative to controls. Encouraging participants to perform an additional 10 min of moderate physical activity under supervision, during ongoing intervention, may be more beneficial to prevent cognitive decline and improve exercise adherence.

Indexed as

dementiadual-taskolder adultsrandomized controlled trial

Identifiers

PMID31261796
PMCPMC6678908
OpenAlexW2955375710

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.