Evidence map›Paper›PMID 31261737›Full record

ArticleNanomaterials (Basel, Switzerland)2019

Osteoblast Biocompatibility and Antibacterial Effects Using 2-Methacryloyloxyethyl Phosphocholine-Grafted Stainless-Steel Composite for Implant Applications.

Dave W Chen, Hsin-Hsin Yu, Li-Jyuan Luo, Selvaraj Rajesh Kumar, Chien-Hao Chen, Tung-Yi Lin, Jui-Yang Lai, Shingjiang Jessie Lue

Open access · goldAbstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Dave W ChenDepartment of Orthopedic Surgery, Chang Gung Memorial Hospital, Keelung City 401, Taiwan.
Hsin-Hsin YuDepartment of Chemical and Materials Engineering and Green Technology Research Center, Chang Gung University, Guishan District, Taoyuan City 333, Taiwan.
Li-Jyuan LuoGraduate institute of Biomedical Engineering, Chang Gung University, Guishan District, Taoyuan City 333, Taiwan.
Selvaraj Rajesh KumarDepartment of Chemical and Materials Engineering and Green Technology Research Center, Chang Gung University, Guishan District, Taoyuan City 333, Taiwan.
Chien-Hao ChenDepartment of Orthopedic Surgery, Chang Gung Memorial Hospital, Keelung City 401, Taiwan.
Tung-Yi LinDepartment of Orthopedic Surgery, Chang Gung Memorial Hospital, Keelung City 401, Taiwan.
Jui-Yang LaiGraduate institute of Biomedical Engineering, Chang Gung University, Guishan District, Taoyuan City 333, Taiwan. jylai@mail.cgu.edu.tw.ORCID 0000-0002-9227-8549
Shingjiang Jessie LueDepartment of Chemical and Materials Engineering and Green Technology Research Center, Chang Gung University, Guishan District, Taoyuan City 333, Taiwan. jessie@mail.cgu.edu.tw.ORCID 0000-0003-1950-8093
Chang Gung University · TWChang Gung University of Science and Technology · TWMing Chi University of Technology · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Poor osteogenesis and bacterial infections lead to an implant failure, so the enhanced osteogenic and antimicrobial activity of the implantable device is of great importance in orthopedic applications. In this study, 2-methacryloyloxyethyl phosphocholine (MPC) was grafted onto 316L stainless steel (SS) using a facile photo-induced radical graft polymerization method via a benzophenone (BP) photo initiator. Atomic force microscopy (AFM) was employed to determine the nanoscale morphological changes on the surface. The grafted BP-MPC layer was estimated to be tens of nanometers thick. The SS-BP-MPC composite was more hydrophilic and smoother than the untreated and BP-treated SS samples.

Indexed as

2-methacryloyloxyethyl phosphocholine (MPC)antibacterial activityorthopedic implantsosseointegrationphoto-induced polymerization

Identifiers

PMID31261737
PMCPMC6669514
OpenAlexW2954054325

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.