Evidence map›Paper›PMID 31261642›Full record

ArticleInternational journal of molecular sciences2019

Real Microgravity Influences the Cytoskeleton and Focal Adhesions in Human Breast Cancer Cells.

Mohamed Zakaria Nassef, Sascha Kopp, Markus Wehland, Daniela Melnik, Jayashree Sahana, Marcus Krüger, Thomas J Corydon, Hergen Oltmann, Burkhard Schmitz, Andreas Schütte and 3 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers.

0numbers the graph read from it
0cells of the map it votes in
66citing papers in PubMed
6.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

66 citing papers in PubMed, 92 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Neutral Buoyancy as a Simple Approach to Simulated Microgravity.Tissue engineering and regenerative medicine · 2026
    Article
  7. Article
  8. Review
  9. Article
  10. Aging and Altered Gravity: A Cellular Perspective.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Imaging actin organisation and dynamics in 3D.Journal of cell science · 2024
    Article

6 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Mohamed Zakaria NassefClinic for Plastic, Aesthetic and Hand Surgery, Otto von Guericke University Magdeburg, D-39120 Magdeburg, Germany.
Sascha KoppClinic for Plastic, Aesthetic and Hand Surgery, Otto von Guericke University Magdeburg, D-39120 Magdeburg, Germany.
Markus WehlandClinic for Plastic, Aesthetic and Hand Surgery, Otto von Guericke University Magdeburg, D-39120 Magdeburg, Germany.
Daniela MelnikClinic for Plastic, Aesthetic and Hand Surgery, Otto von Guericke University Magdeburg, D-39120 Magdeburg, Germany.
Jayashree SahanaDepartment of Biomedicine, Aarhus University, DK-8000 Aarhus C, Denmark.
Marcus KrügerClinic for Plastic, Aesthetic and Hand Surgery, Otto von Guericke University Magdeburg, D-39120 Magdeburg, Germany.ORCID 0000-0003-1120-0246
Thomas J CorydonDepartment of Biomedicine, Aarhus University, DK-8000 Aarhus C, Denmark.
Hergen OltmannAirbus Defence and Space GmbH, Airbus-Allee 1, D-28199 Bremen, Germany.
Burkhard SchmitzAirbus Defence and Space GmbH, Airbus-Allee 1, D-28199 Bremen, Germany.
Andreas SchütteAirbus Defence and Space GmbH, Airbus-Allee 1, D-28199 Bremen, Germany.
Thomas J BauerClinic for Plastic, Aesthetic and Hand Surgery, Otto von Guericke University Magdeburg, D-39120 Magdeburg, Germany.
Manfred InfangerClinic for Plastic, Aesthetic and Hand Surgery, Otto von Guericke University Magdeburg, D-39120 Magdeburg, Germany.
Daniela GrimmClinic for Plastic, Aesthetic and Hand Surgery, Otto von Guericke University Magdeburg, D-39120 Magdeburg, Germany. dgg@biomed.au.dk.
Otto-von-Guericke-Universität Magdeburg · DEAarhus University · DKAirbus (Germany) · DE

Funding

Deutsches Zentrum für Luft- und Raumfahrt 50WB1524Deutsches Zentrum für Luft- und Raumfahrt 50WB1924
6 · The paper itself

Abstract

With the increasing number of spaceflights, it is crucial to understand the changes occurring in human cells exposed to real microgravity (r-µ

Indexed as

Space FlightWeightlessnessActinsBreast NeoplasmsCadherinsCytoskeletonFemaleFocal AdhesionsHumansMCF-7 CellsTubulinVinculinActinsCadherinsTubulinVinculinbreast cancer cellscytoskeletonE-cadherinF-actinfocal adhesionlive-cell imagingmicrogravitytubulinvinculin

Identifiers

PMID31261642
PMCPMC6651518
OpenAlexW2954979301

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.