Evidence map›Paper›PMID 31261621›Full record

ReviewMolecules (Basel, Switzerland)2019

Tissue Transparency In Vivo.

Mikhail Inyushin, Daria Meshalkina, Lidia Zueva, Astrid Zayas-Santiago

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 28 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Mikhail InyushinDepartment of Physiology, Universidad Central del Caribe, Bayamon, PR 00960, USA. mikhail.inyushin@uccaribe.edu.ORCID 0000-0003-3253-7307
Daria MeshalkinaSechenov Institute of Evolutionary Physiology and Biochemistry, St. Petersburg 194064, Russia.
Lidia ZuevaDepartment of Physiology, Universidad Central del Caribe, Bayamon, PR 00960, USA.
Astrid Zayas-SantiagoDepartment of Physiology, Universidad Central del Caribe, Bayamon, PR 00960, USA.ORCID 0000-0003-4028-0564
Central University of the Caribbean · PRInstitute of Evolutionary Physiology and Biochemistry · RU

Funding

Glial uptake of dopamine after L-DOPA medication (hurricane recovery)SC2GM111149 · NIGMS · UNIVERSIDAD CENTRAL DEL CARIBE · PI INYUSHIN, MIKHAIL · 2016 to 2019
$555k
NIGMS NIH HHS SC2 GM111149NIH HHS SC2GM111149
6 · The paper itself

Abstract

In vivo tissue transparency in the visible light spectrum is beneficial for many research applications that use optical methods, whether it involves in vivo optical imaging of cells or their activity, or optical intervention to affect cells or their activity deep inside tissues, such as brain tissue. The classical view is that a tissue is transparent if it neither absorbs nor scatters light, and thus absorption and scattering are the key elements to be controlled to reach the necessary transparency. This review focuses on the latest genetic and chemical approaches for the decoloration of tissue pigments to reduce visible light absorption and the methods to reduce scattering in live tissues. We also discuss the possible molecules involved in transparency.

Indexed as

AnimalsHumansLightOptical ImagingOptogeneticsScattering, Radiationdeep-tissue optogeneticsgenetically modified animalsimaging depthin vivo transparencymodel organisms with transparent tissuesoptical tissue clearing

Identifiers

PMID31261621
PMCPMC6651221
OpenAlexW2955608271

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.