ArticleMaterials (Basel, Switzerland)2019
Synthesis and Characterization of Chitosan/Reduced Graphene Oxide Hybrid Composites.
Article in Materials (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Chitosan-Based Scaffolds for the Treatment of Myocardial Infarction: A Systematic Review.Molecules (Basel, Switzerland) · 2023Pooled it
- Chitosan-graphene oxide films as a promising packaging material for the preservation of fresh plums (RSC advances · 2026Article
- Study of the Influence of Chitosan-Wrapped Carbon Nanotubes on Biopolymer Film Properties.Polymers · 2025Article
- The Diamond Concept Enigma: Recent Trends of Its Implementation in Cross-linked Chitosan-Based Scaffolds for Bone Tissue Engineering.ACS applied bio materials · 2023Review
- A Novel Zwitterionic Hydrogel Incorporated with Graphene Oxide for Bone Tissue Engineering: Synthesis, Characterization, and Promotion of Osteogenic Differentiation of Bone Mesenchymal Stem Cells.International journal of molecular sciences · 2023Article
- Development of Graphene-Based Materials in Bone Tissue Engineaering.Global challenges (Hoboken, NJ) · 2022Review
- Article
- Biomimetic chitosan with biocomposite nanomaterials for bone tissue repair and regeneration.Beilstein journal of nanotechnology · 2022Review
- Functionalized Reduced Graphene Oxide as a Versatile Tool for Cancer Therapy.International journal of molecular sciences · 2021Review
- Fabrication and characterization of mechanically competent 3D printed polycaprolactone-reduced graphene oxide scaffolds.Scientific reports · 2020Article
- Enhancement of Thermal and Mechanical Properties of Bismaleimide Using a Graphene Oxide Modified by Epoxy Silane.Materials (Basel, Switzerland) · 2020Article
- Gradient Chitosan Hydrogels Modified with Graphene Derivatives and Hydroxyapatite: Physiochemical Properties and Initial Cytocompatibility Evaluation.International journal of molecular sciences · 2020Article
- Polylactide/Hydroxyapatite Nonwovens Incorporated into Chitosan/Graphene Materials Hydrogels to Form Novel Hierarchical Scaffolds.International journal of molecular sciences · 2020Article
- Chitosan-Functionalized Graphene Nanocomposite Films: Interfacial Interplay and Biological Activity.Materials (Basel, Switzerland) · 2020Article
- Graphene derivative based hydrogels in biomedical applications.Journal of tissue engineeringReview
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Graphene family materials (GFM) are currently considered to be one of the most interesting nanomaterials with a wide range of application. They can also be used as modifiers of polymer matrices to develop composite materials with favorable properties. In this study, hybrid nanocomposites based on chitosan (CS) and reduced graphene oxide (rGO) were fabricated for potential use in bone tissue engineering. CS/rGO hydrogels were prepared by simultaneous reduction and composite formation in acetic acid or lactic acid and crosslinked with a natural agent-tannic acid (TAc). A broad spectrum of research methods was applied in order to thoroughly characterize both the components and the composite systems, i.e., X-ray Photoelectron Spectroscopy, X-ray Diffractometry, Attenuated Total Reflection Fourier-Transform Infrared Spectroscopy, Scanning Electron Microscopy, ninhydrin assay, mechanical testing, in vitro degradation and bioactivity study, wettability, and, finally, cytocompatibility. The composites formed through the self-assembly of CS chains and exfoliated rGO sheets. Obtained results allowed also to conclude that the type of solvent used impacts the polymer structure and its ability to interact with rGO sheets and the mechanical properties of the composites. Both rGO and TAc acted as crosslinkers of the polymer chains. This study shows that the developed materials demonstrate the potential for use in bone tissue engineering. The next step should be their detailed biological examinations.
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Registered trials
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