ArticleMedicine2019
Effects of brain activity, morning salivary cortisol, and emotion regulation on cognitive impairment in elderly people.
Article in Medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.
- Rhythmic cueing, dance, resistance training, and Parkinson's disease: A systematic review and meta-analysis.Frontiers in neurology · 2022Pooled it
- Effects of aerobic exercise and computer-based cognitive training on cognition, functional independence, quality of life, and salivary cortisol levels in older adults with mild cognitive impairment: a randomized trial.Frontiers in aging neuroscience · 2026Article
- Association between sleep quality and MCI in older adult patients with multimorbidity.Frontiers in public health · 2025Article
- Understanding veterans' experiences with lung cancer and psychological distress: A multimethod approach.Psychological services · 2024Article
- Foreclosure, memory decline, and dementia probability: A longitudinal cohort study.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Article
- The effect of physical exercise during competitions and in simulated conditions on hormonal-neurophysiological relationships in kickboxers.Biology of sport · 2024Article
- Impact of social isolation caused by the COVID-19 pandemic on the mood profile of active and sedentary older adults: physical activity as a protective factor.Frontiers in public health · 2023Observational
- Dissecting the molecular mechanisms underlying the antidepressant activities of herbal medicines through the comprehensive review of the recent literatures.Frontiers in psychiatry · 2022Review
- On the Interplay Between the Medicine of Hildegard of Bingen and Modern Medicine: The Role of Estrogen Receptor as an Example of Biodynamic Interface for Studying the Chronic Disease's Complexity.Frontiers in neuroscience · 2022Article
- Article
- Hair Cortisol Concentration as a Biomarker of Sleep Quality and Related Disorders.Life (Basel, Switzerland) · 2021Review
- Intrauterine Viral Infections: Impact of Inflammation on Fetal Neurodevelopment.Frontiers in neuroscience · 2021Review
- Exercise-Induced Elevated BDNF Level Does Not Prevent Cognitive Impairment Due to Acute Exposure to Moderate Hypoxia in Well-Trained Athletes.International journal of molecular sciences · 2020Article
- [Salivary cortisol concentrations according to gender in the different stages of human development. A review of the literature].Revista cientifica odontologica (Universidad Cientifica del Sur)Review
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveCognitive impairment subjects exhibit high cortisol levels that are associated with low brain activity, but negative emotions with high cortisol are associated with high brain activity and reduced cognition. Emotion regulation, glucocorticoid hormones, and brain activity all interact with cognitive impairment. Therefore, we aimed to investigate cognitive impairment differences related to sex, morning salivary cortisol, emotion regulation, and brain activity in elderly people.
methodsA total of 64 participants (19 males and 45 females) were tested by the Montreal cognitive assessment. Next, morning saliva was collected from each participant and analyzed by enzyme-linked immunosorbent assay, and the brain activity of the participants was subsequently recorded. Finally, emotion regulation was assessed via the Brunel mood scale questionnaire.
resultsThe results revealed that attention was significantly lower in elderly females than in elderly males. Depression and vigor were significantly higher in elderly females than in elderly males. Brain activity of the slow (delta and theta) and fast (beta and high beta) waves was significantly higher in elderly females than in elderly males. Moreover, attention was negatively correlated with the theta wave, whereas delayed recall was positively correlated with the theta wave and salivary cortisol. Depression was positively correlated with the high beta wave and language skill, whereas the high beta wave was negatively correlated with visuoconstructional skill.
conclusionThe brain activity, emotion, and cortisol were influenced by cognitive impairments, although the relation of brain activity with glucocorticoid hormones remains inconclusive. This finding may be useful to the brain aging process, promote healthy brain aging, and prevent neurodegenerative conditions.
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