Evidence map›Paper›PMID 31261226›Full record

ArticleDermatitis : contact, atopic, occupational, drug

Conceptual Model to Illustrate the Symptom Experience and Humanistic Burden Associated With Atopic Dermatitis in Adults and Adolescents.

Laura Grant, Lotte Seiding Larsen, Claire Trennery, Jonathan I Silverberg, William Abramovits, Eric L Simpson, Jean-Francois Stalder, Jean Paty, Julie Hahn-Pedersen, Nana Kragh and 2 more

Abstract read
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Article in Dermatitis : contact, atopic, occupational, drug. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

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  10. Patient education in atopic dermatitis: a scoping review.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2023
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  11. Review
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  19. Antipruritic Effect of Ethyl Acetate Extract fromEvidence-based complementary and alternative medicine : eCAM · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Laura Grant
Lotte Seiding LarsenLEO Pharma A/S, Ballerup, Denmark.
Claire Trennery
Jonathan I SilverbergDepartment of Dermatology, Medical Social Sciences and Preventive Medicine, Northwestern University, Chicago, IL.
William AbramovitsDepartment of Dermatology, Dermatology Treatment and Research Center, Dallas, TX.
Eric L SimpsonDepartment of Dermatology, Oregon Health & Science University, Portland, OR.
Jean-Francois StalderUniversity of Nantes, Département de Médecine Générale et Médecine, Nantes, France.
Jean PatyIQVIA, Pittsburgh, PA.
Julie Hahn-PedersenLEO Pharma A/S, Ballerup, Denmark.
Nana KraghLEO Pharma A/S, Ballerup, Denmark.
Bo BangLEO Pharma A/S, Ballerup, Denmark.
Rob Arbuckle

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atopic dermatitis (AD) is a pruritic or painful dermatologic disease characterized by xerosis and eczema lesions. The symptoms/signs of AD can significantly impact patients' health-related quality of life (HRQoL). This study aimed to qualitatively explore the adult and adolescent experience of AD. A targeted literature review and qualitative concept elicitation interviews with clinicians (n = 5), adult AD patients (n = 28), and adolescent AD patients (n = 20) were conducted to elicit AD signs/symptoms and HRQoL impacts experienced. Verbatim transcripts were analyzed using thematic analysis. Twenty-nine symptoms/signs of AD were reported, including pruritus, pain, erythema, and xerosis. Atopic dermatitis symptoms/signs were reported to substantially impact HRQoL. Scratching was reported to influence the experience of symptoms and HRQoL impacts. Four proximal impacts (including discomfort and sleep disturbance) were reported. Ten domains of distal impact were reported, including impacts on psychological and social functioning and activities of daily living. A conceptual model was developed to summarize these findings. This study highlights the range of symptoms and HRQoL impacts experienced by adults and adolescents with AD. To our knowledge, this study was first to explore the lived experience of AD in both adult and adolescent patients, providing valuable insight into the relatively unexplored adolescent experience of AD.

Indexed as

Cost of IllnessSeverity of Illness IndexActivities of Daily LivingAdolescentAdultDermatitis, AtopicFemaleHealth BehaviorHumansMaleQuality of Life

Identifiers

PMID31261226
PMCPMC6641086

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.