Evidence map›Paper›PMID 31260589›Full record

SynthesisThe British journal of surgery2019

Meta-analysis of the role of colonoscopy after an episode of left-sided acute diverticulitis.

S J Rottier, S T van Dijk, A A W van Geloven, W H Schreurs, W A Draaisma, W A van Enst, J B C M Puylaert, M G J de Boer, B R Klarenbeek, J A Otte and 2 more

Open access · hybridAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in The British journal of surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 3 pooled it
6.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 3 syntheses or guidelines pooled it, 52 citations in OpenAlex.

  1. Guideline
  2. Pooled it
  3. Antibiotics for uncomplicated diverticulitis.The Cochrane database of systematic reviews · 2022
    Pooled it
  4. Trial
  5. Trial
  6. Review
  7. Utility of Colonoscopy After Acute Colonic Diverticulitis.Diagnostics (Basel, Switzerland) · 2026
    Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Antibiotics for acute diverticulitis.Canadian family physician Medecin de famille canadien · 2025
    Article
  14. Article
  15. Follow-Up Colonoscopy for Detection of Missed Colorectal Cancer After Diverticulitis.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2024
    Article
  16. Contemporary management of diverticulitis.Surgery open science · 2024
    Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 2 countries.

S J RottierDepartment of Surgery, Northwest Clinics, Alkmaar, the Netherlands.ORCID 0000-0003-4996-8162
S T van DijkDepartments of Surgery, Amsterdam UMC, Amsterdam, the Netherlands.
A A W van GelovenDepartment of Surgery, Tergooi Hospital, Hilversum, the Netherlands.
W H SchreursDepartment of Surgery, Northwest Clinics, Alkmaar, the Netherlands.
W A DraaismaDepartment of Surgery, Jeroen Bosch Hospital, 's-Hertogenbosch, the Netherlands.
W A van EnstKnowledge Institute of Medical Specialists, Utrecht, the Netherlands.
J B C M PuylaertDepartment of Radiology, Haaglanden Medical Centre, The Hague.
M G J de BoerDepartment of Infectious Diseases, Leiden University Medical Centre, Leiden, the Netherlands.
B R KlarenbeekDepartment of Surgery, Radboud University Medical Centre, Nijmegen, the Netherlands.
J A OtteDepartment of Internal Medicine, ZorgSaam Hospital, Terneuzen, the Netherlands.
R J F FeltDepartments of Gastroenterology, Amsterdam UMC, Amsterdam, the Netherlands.
M A BoermeesterDepartments of Surgery, Amsterdam UMC, Amsterdam, the Netherlands.
Amsterdam University Medical Centers · NLNorthwest Hospital · USJeroen Bosch Ziekenhuis · NLLeiden University Medical Center · NLMedisch Centrum Haaglanden · NLRadboud University Nijmegen · NLTergooi · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRoutine colonoscopy was traditionally recommended after acute diverticulitis to exclude coexistent malignancy. Improved CT imaging may make routine colonoscopy less required over time but most guidelines still recommend it. The aim of this review was to assess the role of colonoscopy in patients with CT-proven acute diverticulitis.

methodsPubMed and Embase were searched for studies reporting the prevalence of advanced colorectal neoplasia (ACN) or colorectal carcinoma in patients who underwent colonoscopy within 1 year after CT-proven left-sided acute diverticulitis. The prevalence was pooled using a random-effects model and, if possible, compared with that among asymptomatic controls.

resultsSeventeen studies with 3296 patients were included. The pooled prevalence of ACN was 6·9 (95 per cent c.i. 5·0 to 9·4) per cent and that of colorectal carcinoma was 2·1 (1·5 to 3·1) per cent. Only two studies reported a comparison with asymptomatic controls, showing comparable risks (risk ratio 1·80, 95 per cent c.i. 0·66 to 4·96). In subgroup analysis of patients with uncomplicated acute diverticulitis, the prevalence of colorectal carcinoma was only 0·5 (0·2 to 1·2) per cent.

conclusionRoutine colonoscopy may be omitted in patients with uncomplicated diverticulitis if CT imaging is otherwise clear. Patients with complicated disease or ongoing symptoms should undergo colonoscopy.

Indexed as

ColonoscopyAcute DiseaseColorectal NeoplasmsDiverticulitisHumansPrevalenceTomography, X-Ray Computed

Identifiers

PMID31260589
PMCPMC6618242
OpenAlexW2955486472

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.