ArticlePloS one2019
Implementation of latent tuberculosis infection screening and treatment among newly arriving immigrants in the Netherlands: A mixed methods pilot evaluation.
Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 4 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 4 syntheses or guidelines pooled it, 49 citations in OpenAlex.
- Acceptance of preventive therapy for latent tuberculosis infection in Chinese children and adolescents: a systematic review and meta-analysis.Scientific reports · 2025Pooled it
- Barriers and facilitators of tuberculosis treatment among immigrants: an integrative review.BMC public health · 2024Pooled it
- Mandatory, voluntary, repetitive, or one-off post-migration follow-up for tuberculosis prevention and control: A systematic review.PLoS medicine · 2023Pooled it
- Initiation and completion of treatment for latent tuberculosis infection in migrants globally: a systematic review and meta-analysis.The Lancet. Infectious diseases · 2021Pooled it
- Treatment of latent tuberculosis infection in migrants in primary careThe European respiratory journal · 2024Trial
- Stigma among patients with TB infection in a low-TB-burden setting.IJTLD open · 2026Article
- Uncovering Household Tuberculosis Infection Testing and Care Patterns Using a Novel Bioinformatics Linkage Strategy.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2026Article
- Measuring recent in-country TB transmission using a classification model with whole genome sequencing data.IJTLD open · 2026Article
- Barriers and enablers of TB infection screening and treatment programme for recent migrants in East London.Public health action · 2026Article
- Enhanced screening for tuberculosis infection among immigrants in southern New Brunswick: A cross-sectional pilot study.Canada communicable disease report = Releve des maladies transmissibles au Canada · 2025Article
- The impact of latent tuberculosis screening programmes for migrant populations in high income, low burden countries.PloS one · 2025Article
- A synthesis of qualitative evidence of barriers and facilitators in implementing guidelines for TB testing in healthcare settings.Implementation science communications · 2024Review
- Article
- Tuberculosis screening in the European migrant population: a scoping review of current practices.Breathe (Sheffield, England) · 2024Article
- Pediatric Tuberculosis Infection Care Facilitators and Barriers: A Qualitative Study.Pediatrics · 2024Article
- "It's too hard" - the management of latent TB in under-served populations in the UK: a qualitative study.BMC health services research · 2022Article
- Fragmentation of Healthcare Services as a Possible Determinant of the Low Completion for the Tuberculosis Cascade of Prevention among Asylum Seekers: Results from a Prospective Study with Historical Comparison.Pathogens (Basel, Switzerland) · 2022Article
- A scoping review of paediatric latent tuberculosis infection care cascades: initial steps are lacking.BMJ global health · 2021Article
- Knowledge, attitudes, beliefs, and stigma related to latent tuberculosis infection: a qualitative study among Eritreans in the Netherlands.BMC public health · 2020Article
- [Contact tracing in patients infected with SARS-CoV-2. The fundamental role of Primary Health Care and Public Health].Semergen · 2020Review
Corrections and comments
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Authors and funding
9 authors at 6 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionTo reach pre-elimination levels of tuberculosis (TB) incidence in the Netherlands, prevention of TB among immigrants through diagnosis and treatment of latent TB infection (LTBI) is needed. We studied the feasibility of a LTBI screening and treatment program among newly arriving immigrants for national implementation.
methodsWe used mixed methods to evaluate the implementation of LTBI screening and treatment in five Public Health Services (PHS) among immigrants from countries with a TB incidence >50/100,000 population. We used Poisson regression models with robust variance estimators to assess factors associated with LTBI diagnosis and LTBI treatment initiation and reported reasons for not initiating or completing LTBI treatment. We interviewed five PHS teams using a semi-structured method to identify enhancing and impeding factors for LTBI screening and treatment.
resultsWe screened 566 immigrants; 94 (17%) were diagnosed with LTBI, of whom 49 (52%) initiated and 34 (69%) completed LTBI treatment. LTBI diagnosis was associated with male gender, higher age group, higher TB incidence in the country of origin and lower level of education. Treatment initiation was associated with PHS (ranging from 29% to 86%), lower age group, longer intended duration of stay in the Netherlands, and lower level of education. According to TB physicians, clients and their consulted physicians in the home country lacked awareness about benefits of LTBI treatment. Furthermore, TB physicians questioned the individual and public health benefit of clients who return to their country of origin within the foreseeable future.
conclusionsDoubt of physicians in both host country and country of origin about individual and public health benefits of LTBI screening and treatment of immigrants hampered treatment initiation: the high initiation proportion in one PHS shows that if TB physicians are committed, the LTBI treatment uptake can be higher.
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