ArticlePloS one2019
Influenza vaccination and secondary prevention of cardiovascular disease among Taiwanese elders-A propensity score-matched follow-up study.
Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 5 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 5 syntheses or guidelines pooled it, 44 citations in OpenAlex.
- Influenza vaccination and the risk of myocardial infarction: a meta-epidemiology study.BMC public health · 2026Pooled it
- The benefits of influenza vaccination in patients with cardiovascular disease: a systematic review and meta-analysis.Frontiers in pharmacology · 2025Pooled it
- Impact of influenza, herpes zoster, and pneumococcal vaccinations on the incidence of cardiovascular events in subjects aged over 65 years: a systematic review.GeroScience · 2023Pooled it
- Effects of Influenza Vaccine on Mortality and Cardiovascular Outcomes in Patients With Cardiovascular Disease: A Systematic Review and Meta-Analysis.Journal of the American Heart Association · 2021Pooled it
- Protective effect of influenza vaccination on cardiovascular diseases: a systematic review and meta-analysis.Scientific reports · 2020Pooled it
- Effects of Respiratory Vaccines in Older Adults with Cardiovascular Diseases: A Scoping Review.Vaccines · 2026Review
- Influenza vaccination in patients with heart failure: comprehensive review of evidence, challenges, and clinical implications.Heart failure reviews · 2026Review
- Estimating cardiovascular effects of influenza vaccination in older adults: a target trial emulation using proximal causal inference.EClinicalMedicine · 2025Article
- 2025 Expert Consensus Recommendations on Vaccinations in Adults with High Cardiovascular Risk and Cardiovascular Disease: A Report of the Task Force of the Taiwan Society of Cardiology and the Infectious Diseases Society of Taiwan.Acta Cardiologica Sinica · 2025Article
- [Vaccination and cardiovascular diseases].Herz · 2025Review
- 2024 Guidelines of the Taiwan Society of Cardiology for the Diagnosis and Treatment of Heart Failure with Preserved Ejection Fraction.Acta Cardiologica Sinica · 2024Article
- Vaccines and cardiovascular outcomes: lessons learned from influenza epidemics.European heart journal supplements : journal of the European Society of Cardiology · 2023Article
- 2023 Guidelines of the Taiwan Society of Cardiology on the Diagnosis and Management of Chronic Coronary Syndrome.Acta Cardiologica Sinica · 2023Article
- Air Pollution Exposure and the Relative Risk of Sudden Sensorineural Hearing Loss in Taipei.International journal of environmental research and public health · 2022Observational
- [Influenza and cardiorespiratory events: a clinical-epidemiological review with a multidisciplinary point of view].Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2021Review
- Review
- The role of angiotensin-converting enzyme 2 in coronaviruses/influenza viruses and cardiovascular disease.Cardiovascular research · 2020Review
- Relationship between Influenza Vaccination Coverage Rate and COVID-19 Outbreak: An Italian Ecological Study.Vaccines · 2020Article
- Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The present study aimed to evaluate the association between influenza vaccination and the secondary prevention of cardiovascular disease (CVD) among elderly persons. This retrospective cohort study used the Geriatric Dataset of Taiwan's National Health Insurance Research Database (2000-2013). Patients aged ≥ 65 years who had been hospitalized for the first episodes of myocardial infarction were eligible. The vaccinated cohort comprised patients who received one dose of influenza vaccine within 180 days after discharge. The unvaccinated cohort included those who did not receive influenza vaccination and was propensity score-matched (1:1) for known CVD risk factors. All-cause death, acute myocardial infarction or cardiovascular death, and hospitalization for heart failure were assessed 1 year after the 181st day after hospital discharge. Compared with the matched cohort (n = 4,350), the vaccinated cohort (n = 4,350) had significantly lower incidences of all-cause death (hazard ratios [HR] 0.82, 95% CI [confidence interval] 0.73-0.92), myocardial infarction or cardiovascular death (HR 0.84, 95% CI 0.74-0.96), and hospitalization for heart failure (HR 0.83, 95% CI 0.74-0.92). The association between influenza vaccination and reduction of CVDs was similar across different subgroups. Cumulative incidence curves of the CVDs of interest for the two cohorts separated within the initial 3 months of follow-up (P < 0.05). Influenza vaccination was associated with a reduced risk of CVD in the elderly population with previous myocardial infarction.
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