Evidence map›Paper›PMID 31259767›Full record

ArticleAIDS (London, England)2019

HIV stigma and viral load among African-American women receiving treatment for HIV.

Christopher G Kemp, Lauren Lipira, David Huh, Paul E Nevin, Janet M Turan, Jane M Simoni, Susan E Cohn, Mieoak Bahk, Baiba Berzins, Michele Andrasik and 2 more

Abstract read
In one paragraph

Article in AIDS (London, England), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Christopher G KempDepartment of Global Health.
Lauren LipiraDepartment of Health Services.
David HuhSchool of Social Work.
Paul E NevinDepartment of Global Health.
Janet M TuranSchool of Public Health, University of Alabama at Birmingham, Birmingham, Alabama.
Jane M SimoniDepartment of Global Health.
Susan E CohnDivision of Infectious Diseases, Northwestern University Feinberg School of Medicine.
Mieoak BahkRuth M. Rothstein CORE Center, Chicago, Illinois.
Baiba BerzinsDivision of Infectious Diseases, Northwestern University Feinberg School of Medicine.
Michele AndrasikDepartment of Global Health.
Michael J MugaveroDepartment of Medicine, School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama.
Deepa RaoDepartment of Global Health.

Funding

University of Washington/Fred Hutch Center for AIDS ResearchP30AI027757 · NIAID · UNIVERSITY OF WASHINGTON · PI Judith Tsui · 1988 to 2026
$104.9M
Reducing HIV Stigma to Improve Health Outcomes for African-American WomenR01MH098675 · NIMH · UNIVERSITY OF WASHINGTON · PI RAO, DEEPA · 2012 to 2016
$2.6M
Strengthening the Integration of Mental Health and HIV Services in South Africa: Implementation Science in Support of Scale-Up, Adaptation, and DisseminationF31MH112397 · NIMH · UNIVERSITY OF WASHINGTON · PI KEMP, CHRISTOPHER G · 2017 to 2018
$79k
NIAID NIH HHS P30 AI027757NIMH NIH HHS F31 MH112397NIMH NIH HHS R01 MH098675
6 · The paper itself

Abstract

objectiveAfrican-American women are more likely than other women in the United States to experience poor HIV-related health; HIV stigma may contribute to these outcomes. This study assessed the relationship between HIV stigma and viral load, over time, among a sample of African-American women receiving treatment for HIV, and explored social support and depressive symptoms as mediators.

designSecondary analysis of longitudinal data.

methodsData came from a randomized trial of an intervention to reduce HIV stigma among African-American women in HIV care in Chicago, Illinois and Birmingham, Alabama. Sociodemographic and psychosocial data were collected at up to six study visits over 14 months. Viral loads were extracted from medical records during the study period. Generalized linear mixed effects models were used to estimate associations among overall, internalized, and enacted HIV stigma and viral load over time. Mediation analyses were used to estimate indirect effects via social support and depressive symptoms.

resultsData from 234 women were analyzed. Overall HIV stigma was significantly associated with subsequent viral load (adjusted β = 0.24, P = 0.005). Both between-subject (adjusted β = 0.74, P < 0.001) and within-subject (adjusted β = 0.34, P = 0.005) differences in enacted stigma were associated with viral load. Neither social support nor depressive symptoms were statistically significant mediators.

conclusionOngoing experiences of HIV stigmatization may contribute to increased viral load among African-American women in primary HIV care. Interventions should aim to alleviate the consequences of stigma experienced by patients and prevent future stigmatization.

Indexed as

Social StigmaAdolescentAdultAgedAged, 80 and overAlabamaAnti-Retroviral AgentsBlack or African AmericanChicagoFemaleHIV InfectionsHumansMiddle AgedPatient Acceptance of Health CareTreatment OutcomeViral LoadAnti-Retroviral Agents

Identifiers

PMID31259767
PMCPMC6621603

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.