Evidence map›Paper›PMID 31259765›Full record

ArticleAIDS (London, England)2019

Homelessness at diagnosis is associated with death among people with HIV in a population-based study of a US city.

Matthew A Spinelli, Nancy A Hessol, Sandy Schwarcz, Ling Hsu, Maree-Kay Parisi, Sharon Pipkin, Susan Scheer, Diane Havlir, Susan P Buchbinder

Abstract read
In one paragraph

Article in AIDS (London, England), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

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  10. Identifying Missed Opportunities for Routine Vaccination among People Who Use Drugs.International journal of environmental research and public health · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Matthew A SpinelliDivision of HIV, ID, and Global Medicine.
Nancy A HessolDepartment of Clinical Pharmacy and of Medicine, University of California, San Francisco.
Sandy SchwarczSan Francisco Department of Public Health, San Francisco, California, USA.
Ling HsuSan Francisco Department of Public Health, San Francisco, California, USA.
Maree-Kay ParisiSan Francisco Department of Public Health, San Francisco, California, USA.
Sharon PipkinSan Francisco Department of Public Health, San Francisco, California, USA.
Susan ScheerSan Francisco Department of Public Health, San Francisco, California, USA.
Diane HavlirDivision of HIV, ID, and Global Medicine.
Susan P BuchbinderSan Francisco Department of Public Health, San Francisco, California, USA.

Funding

San Francisco Vaccine and Prevention UnitUM1AI069496 · NIAID · PUBLIC HEALTH FOUNDATION ENTERPRISES · PI Susan Buchbinder, Diane V Havlir · 2012 to 2026
$30.5M
Training in HIV Translational ResearchT32AI060530 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Diane V Havlir · 2005 to 2026
$6.4M
NIAID NIH HHS T32 AI060530NIAID NIH HHS UM1 AI069496
6 · The paper itself

Abstract

objectiveSan Francisco, California, has experienced a 44% reduction in new HIV diagnoses since 2013 supported by its 'Getting to Zero' initiative; however, the age-adjusted mortality rate in people with HIV (PWH) has not decreased. We sought to identify factors associated with death among PWH in San Francisco.

designPopulation-based incidence-density case-control study.

methodsAmong PWH in the San Francisco HIV surveillance registry, a random sample of 48 decedents from 1 July 2016 to 31 May 2017 were each matched to two to three controls who were alive at the date of death (108 controls matched on age and time since diagnosis). Covariates included demographics, substance use, housing status, medical conditions, and care indicators from the study population. We used matched-pair conditional logistic regression to examine factors associated with mortality.

resultsOf the 156 PWH in the study, 14% were African-American, 14% Latino, and 8% female sex. In adjusted analysis, factors associated with higher odds of death included: homelessness at HIV diagnosis [adjusted odds ratio (AOR) = 27.4; 95% confidence interval (CI) = 3.0-552.1], prior-year IDU (AOR = 10.2; 95% CI = 1.7-128.5), prior-year tobacco use (AOR = 7.2; 95% CI = 1.7-46.9), being off antiretroviral therapy at any point in the prior year (AOR = 6.8; 95% CI = 1.1-71.4), and being unpartnered vs. married/partnered (AOR = 4.7; 95% CI = 1.3-22.0).

conclusionPeople homeless at HIV diagnosis had 27-fold higher odds of death compared with those with housing; substance use and retention on antiretroviral therapy in the prior year are other important intervenable factors. New strategies to address these barriers, and continued investment in supportive housing and substance use treatment, are needed.

Indexed as

AdultAgedAged, 80 and overCase-Control StudiesFemaleHIV InfectionsHousingHumansIll-Housed PersonsLogistic ModelsMaleMiddle AgedMortalitySan Francisco

Identifiers

PMID31259765
PMCPMC6663574

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.