Evidence map›Paper›PMID 31259647›Full record

ArticleJournal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics

The Efficacy of 2% Topical Rebamipide on Conjunctival Squamous Metaplasia and Goblet Cell Density in Dry Eye Disease.

Cem Simsek, Murat Dogru, Megumi Shinzawa, Seika Den, Takashi Kojima, Hiroyuki Iseda, Mai Suzuki, Yoshiyuki Shibasaki, Naoshi Yoshida, Jun Shimazaki

Open access · hybridAbstract read
In one paragraph

Article in Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Rebamipide in gastric mucosal protection and healing: An Asian perspective.World journal of gastrointestinal pharmacology and therapeutics · 2025
    Review
  4. Article
  5. The Role of In Vivo Confocal Microscopy in Ocular Allergies.Turkish journal of ophthalmology · 2024
    Review
  6. Review
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Cem Simsek1Department of Ophthalmology, Keio University School of Medicine, Tokyo, Japan.
Murat Dogru1Department of Ophthalmology, Keio University School of Medicine, Tokyo, Japan.
Megumi Shinzawa1Department of Ophthalmology, Keio University School of Medicine, Tokyo, Japan.
Seika Den2Department of Ophthalmology, Tokyo Dental College, Ichikawa General Hospital, Chiba, Japan.
Takashi Kojima1Department of Ophthalmology, Keio University School of Medicine, Tokyo, Japan.
Hiroyuki Iseda2Department of Ophthalmology, Tokyo Dental College, Ichikawa General Hospital, Chiba, Japan.
Mai Suzuki2Department of Ophthalmology, Tokyo Dental College, Ichikawa General Hospital, Chiba, Japan.
Yoshiyuki Shibasaki3Department of Medical Affairs, Otsuka Pharmaceutical Co., Ltd., Tokyo, Japan.
Naoshi Yoshida3Department of Medical Affairs, Otsuka Pharmaceutical Co., Ltd., Tokyo, Japan.
Jun Shimazaki2Department of Ophthalmology, Tokyo Dental College, Ichikawa General Hospital, Chiba, Japan.
Keio University · JPTokyo Dental College Ichikawa General Hospital · JPOtsuka (Japan) · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Administration, OphthalmicAlanineConjunctivaDry Eye SyndromesFemaleGoblet CellsHumansMaleMetaplasiaMiddle AgedQuinolonesTreatment OutcomeAlanineQuinolonesrebamipidedry eye syndromeocular surfacerebamipidesquamous metaplasia

Identifiers

PMID31259647
PMCPMC6659741
OpenAlexW2955953046

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.