Evidence map›Paper›PMID 31259645›Full record

SynthesisActa orthopaedica2019

Failure modes of patellofemoral arthroplasty-registries vs. clinical studies: a systematic review.

Nikolaj B Bendixen, Peter W Eskelund, Anders Odgaard

Registry-linked trialAbstract readSystematic Review
In one paragraph

Synthesis in Acta orthopaedica, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04772625 (Failure Analysis of Patellofemoral Arthroplasty), which is not on this map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04772625 active not recruitingnot on this map

Failure Analysis of Patellofemoral Arthroplasty

TypeobservationalSponsorAnders OdgaardRan2019 to 2026Enrolled550ConditionsPatellofemoral Osteoarthritis, Arthroplasty Complications, Knee OsteoarthritisArmsPatellofemoral arthroplasty
3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. [Patellofemoral joint replacement: onlay or inlay?]Orthopadie (Heidelberg, Germany) · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Contemporary knee arthroplasty: one fits all or time for diversity?Archives of orthopaedic and trauma surgery · 2021
    Review
  13. Review
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Nikolaj B BendixenDepartment of Orthopedic Surgery, Copenhagen University Hospital Herlev-Gentofte , Hellerup , Denmark.
Peter W EskelundDepartment of Orthopedic Surgery, Copenhagen University Hospital Herlev-Gentofte , Hellerup , Denmark.
Anders OdgaardDepartment of Orthopedic Surgery, Copenhagen University Hospital Herlev-Gentofte , Hellerup , Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and purpose - Patellofemoral arthroplasty (PFA) has been debated since early studies showed poor implant survival. Recent studies show better results. This review reports failure modes for PFA and investigates differences in data reported from registries and clinical studies. Additionally, we report differences in failure modes among implant designs. Methods - A systematic search was performed in September 2018. All studies and registers describing failure modes of PFA were included and implant design was noted for each revision. Results - This review includes 1,299 revisions of a primary PFA reported in 47 clinical studies and 3 registers. The failure modes were: 42% OA progression, 16% pain, 13% aseptic loosening, 12% surgical error, 4% wear, 2% infection, 2% broken patellar component, 1% stiffness, 1% fracture, and 7% other. The data from registries and cohort studies differed statistically significantly in 7 out of 12 failure modes. Significant differences were found in several failure modes among implant designs. Interpretation - OA progression is the most common failure mode of PFA. There are significant differences in data on failure modes between registers and protocolled studies, notably for surgical error. The implant design significantly influences several of the failure modes. In conclusion, indication, surgical technique, and implant design are important for a successful PFA, and register-based failure modes should be interpreted with caution.

Indexed as

Arthroplasty, Replacement, KneeHumansKnee ProsthesisPatellofemoral JointProsthesis DesignProsthesis FailureRegistriesReoperationResearch DesignRisk Factors

Identifiers

PMID31259645
PMCPMC6746256

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.