Evidence map›Paper›PMID 31259306›Full record

ArticleJournal of Alzheimer's disease reports2019

Mild Cognitive Impairment with a High Risk of Progression to Alzheimer's Disease Dementia (MCI-HR-AD): Effect of Souvenaid

Maria Sagrario Manzano Palomo, Belen Anaya Caravaca, Maria Angeles Balsa Bretón, Sergio Muñiz Castrillo, Asuncion de la Morena Vicente, Eduardo Castro Arce, María Teresa Alves Prez

Open access · diamondAbstract read
In one paragraph

Article in Journal of Alzheimer's disease reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Nutritional metabolism and cerebral bioenergetics in Alzheimer's disease and related dementias.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2023
    Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Maria Sagrario Manzano PalomoDepartment of Neurology, Infanta Leonor Hospital, Madrid, Spain.
Belen Anaya CaravacaNeuropsychologist, Infanta Cristina Hospital, Parla, Madrid, Spain.
Maria Angeles Balsa BretónDepartment of Nuclear Medicine, Getafe Hospital, Madrid, Spain.
Sergio Muñiz CastrilloDepartment of Neurology, Infanta Cristina Hospital, Parla, Madrid, Spain.
Asuncion de la Morena VicenteDepartment of Neurology, Infanta Cristina Hospital, Parla, Madrid, Spain.
Eduardo Castro ArceNutricia NeuroScience Medical Affairs, Madrid, Spain.
María Teresa Alves PrezNutricia Advanced Medical Nutrition, Madrid, Spain.
Hospital Universitario Infanta Cristina · ESHospital Universitario de Getafe · ESSpanish Society of Family and Community Medicine · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPrevious studies have shown that Souvenaid (medical food) can have benefits on memory, cognition, and function in early Alzheimer's disease (AD) and mild cognitive impairment (MCI).

objectiveDemonstrate that Souvenaid could improve or maintain cognition and has an effect on neurodegeneration biomarkers.

methodsThis cohort study was carried out from June 2015 through December 2016 in the Neurology Department, Infanta Cristina Hospital, Madrid, Spain. MCI-HR-AD were recruited using Petersen criteria, neuropsychology (NPS), and

resultsSubjects included 43 MCI patients (58.5% women; mean age 69.78±7.89): 17 receiving Souvenaid

conclusionSouvenaid had a significant effect on several cognitive domains, and on SCS in patients with MCI-HR-AD. Its intervention had an impact on preservation on

Indexed as

18F-FDG PET scansAlzheimer’s diseasemild cognitive impairmentneuropsychologySouvenaid®

Identifiers

PMID31259306
PMCPMC6597964
OpenAlexW2942994066

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.