Evidence map›Paper›PMID 31259305›Full record

ArticleJournal of Alzheimer's disease reports2019

Pre-Clinical Safety and Efficacy Evaluation of Amytrap, a Novel Therapeutic to Treat Alzheimer's Disease.

Omkar Gandbhir, Pazhani Sundaram

Abstract read
In one paragraph

Article in Journal of Alzheimer's disease reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Recent Applications of Retro-Inverso Peptides.International journal of molecular sciences · 2021
    Review
  3. Novel API Coated Catheter Removes Amyloid-β from Plasma of Patients with Alzheimer's Disease.HSOA journal of alzheimer's & neurodegenerative diseases · 2021
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Omkar GandbhirRecombinant Technologies, Cheshire, CT, USA.
Pazhani SundaramRecombinant Technologies, Cheshire, CT, USA.

Funding

SMALL MOLECULE THERAPY FOR ALZHEIMER'S DISEASER44AG050336 · NIA · RECOMBINANT TECHNOLOGIES, LLC · PI SUNDARAM, PAZHANI · 2016 to 2018
$1.7M
Detoxification Depot for Beta-amyloid peptidesR43AG023457 · NIA · RECOMBINANT TECHNOLOGIES, LLC · PI SUNDARAM, PAZHANI · 2003 to 2003
$150k
NIA NIH HHS R43 AG023457NIA NIH HHS R44 AG050336
6 · The paper itself

Abstract

Alzheimer's disease (AD) is the most common cause of dementia. Amyloid-β (Aβ

Indexed as

Alzheimer’s diseaseamyloidamyloid-β binderAmytrapefficacypeptideretro inverso peptidetherapytoxicology

Identifiers

PMID31259305
PMCPMC6597960

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.