Evidence map›Paper›PMID 31259038›Full record

ArticleAMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science2019

Predictive Modeling of the Risk of Acute Kidney Injury in Critical Care: A Systematic Investigation of The Class Imbalance Problem.

Zhenxing Xu, Yujuan Feng, Yun Li, Anand Srivastava, Prakash Adekkanattu, Jessica S Ancker, Guoqian Jiang, Richard C Kiefer, Kathleen Lee, Jennifer A Pacheco and 4 more

Abstract read
In one paragraph

Article in AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Validation of a cancer population derived AKI machine learning algorithm in a general critical care scenario.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2025
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Knowledge Graph Embeddings for ICU readmission prediction.BMC medical informatics and decision making · 2023
    Article
  8. Improving suicide risk prediction via targeted data fusion: proof of concept using medical claims data.Journal of the American Medical Informatics Association : JAMIA · 2022
    Article
  9. Integration of NLP2FHIR Representation with Deep Learning Models for EHR Phenotyping: A Pilot Study on Obesity Datasets.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Zhenxing XuWeill Cornell Medicine, Cornell University, New York, NY, USA.
Yujuan FengDepartment of Computer Science and Engineering, Tsinghua University, Beijing, China.
Yun LiNorthwestern University Feinberg School of Medicine, Chicago, IL, USA.
Anand SrivastavaNorthwestern University Feinberg School of Medicine, Chicago, IL, USA.
Prakash AdekkanattuWeill Cornell Medicine, Cornell University, New York, NY, USA.
Jessica S AnckerWeill Cornell Medicine, Cornell University, New York, NY, USA.
Guoqian JiangMayo Clinic, Rochester, MN, USA.
Richard C KieferMayo Clinic, Rochester, MN, USA.
Kathleen LeeWeill Cornell Medicine, Cornell University, New York, NY, USA.
Jennifer A PachecoNorthwestern University Feinberg School of Medicine, Chicago, IL, USA.
Luke V RasmussenNorthwestern University Feinberg School of Medicine, Chicago, IL, USA.
Jyotishman PathakWeill Cornell Medicine, Cornell University, New York, NY, USA.
Yuan LuoNorthwestern University Feinberg School of Medicine, Chicago, IL, USA.
Fei WangWeill Cornell Medicine, Cornell University, New York, NY, USA.

Funding

National Infrastructure for Standardized and Portable EHR Phenotyping AlgorithmsR01GM105688 · NIGMS · WEILL MEDICAL COLL OF CORNELL UNIV · PI LUO, YUAN, PATHAK, JYOTISHMAN · 2013 to 2020
$5.7M
Bayesian Generative Methods for Extracting and Modeling Relations in EHR NarrativesR21LM012618 · NLM · NORTHWESTERN UNIVERSITY AT CHICAGO · PI LUO, YUAN · 2017 to 2018
$390k
NIGMS NIH HHS R01 GM105688NLM NIH HHS R21 LM012618
6 · The paper itself

Abstract

Acute Kidney Injury (AKI) in critical care is often a quickly-evolving clinical event with high morbidity and mortality. Early prediction of AKI risk in critical care setting can facilitate early interventions that are likely to provide ben- efit. Recently there have been some research on AKI prediction with patient Electronic Health Records (EHR). The class imbalance problem is encountered in such prediction setting where the number of AKI cases is usually much smaller than the controls. This study systematically investigates the impact of class imbalance on the performance of AKI prediction. We systematically investigate several class-balancing strategies to address class imbalance, includ- ing traditional statistical approaches and the proposed methods (case-control matching approach and individualized prediction approach). Our results show that the proposed class-balancing strategies can effectively improve the AKI prediction performance. Additionally, some important predictors (e.g., creatinine, chloride, and urine) for AKI can be found based on the proposed methods.

Identifiers

PMID31259038
PMCPMC6568062

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.