Evidence map›Paper›PMID 31258916›Full record

Trial reportBMJ open respiratory research2019

Pilot study: an intensive care unit sleep promotion protocol.

Melissa P Knauert, Margaret Pisani, Nancy Redeker, Terry Murphy, Katy Araujo, Sangchoon Jeon, Henry Yaggi

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in BMJ open respiratory research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Observational
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Sleep and critical illness: a review.Frontiers in medicine · 2023
    Review
  12. Review
  13. Article
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Melissa P KnauertSection of Pulmonary, Critical Care, and Sleep Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.ORCID 0000-0002-7341-850X
Margaret PisaniSection of Pulmonary, Critical Care, and Sleep Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.
Nancy RedekerDivision of Acute Care/Health Systems, Yale School of Nursing, Yale University, New Haven, Connecticut, USA.
Terry MurphySection of Geriatrics, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.
Katy AraujoSection of Geriatrics, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.
Sangchoon JeonDivision of Acute Care/Health Systems, Yale School of Nursing, Yale University, New Haven, Connecticut, USA.
Henry YaggiSection of Pulmonary, Critical Care, and Sleep Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.

Funding

Yale Study Support Suite (YES3): Dashboard and Web Portal Software Supporting Research Workflow through integrated, customizable REDCap External ModulesP30AG021342 · NIA · YALE UNIVERSITY · PI Denise Esserman · 2002 to 2026
$37.9M
Yale University Clinical and Translational Science Award ProgramKL2TR000140 · NCATS · YALE UNIVERSITY · PI SHERWIN, ROBERT S · 2012 to 2015
$2.9M
Yale Center for Sleep Disturbance in Acute and Chronic ConditionsP20NR014126 · NINR · YALE UNIVERSITY · PI REDEKER, NANCY S, YAGGI, HENRY KLAR · 2012 to 2016
$1.4M
Circadian Rhythm as a Novel Therapeutic Target in the Intensive Care UnitK23HL138229 · NHLBI · YALE UNIVERSITY · PI KNAUERT, MELISSA P · 2018 to 2021
$746k
Mentoring in Sleep Research and Sleep Interventions in Heart Disease, and StrokeK24HL132093 · NHLBI · YALE UNIVERSITY · PI YAGGI, HENRY KLAR · 2016 to 2020
$336k
NCATS NIH HHS KL2 TR000140NHLBI NIH HHS K23 HL138229NHLBI NIH HHS K24 HL132093NIA NIH HHS P30 AG021342NINR NIH HHS P20 NR014126
6 · The paper itself

Abstract

Purpose: Disturbances, such as in-room activity and sound, are significant sources of sleep disruption among critically ill patients. These factors are potentially modifiable. We tested the impact of an intensive care unit (ICU) sleep promotion protocol on overnight in-room disturbance. Methods: Our protocol restricted non-urgent bedside care from 00:00 to 03:59. Patients were assigned to usual care (n=30) or the sleep protocol (n=26). The primary outcomes were measures of in-room activity, sound and light. These three types of disturbance were compared between arms during a baseline time block (20:00-23:59) and a rest time block (00:00-03:59). We assessed the sleep protocol effect with generalised linear models. Results: Usual care and sleep protocol patients had equivalent levels of in-room activity, sound and light during the baseline time block (20:00-23:59). In contrast, during the rest time block (00:00-03:59), the sleep protocol arm had 32% fewer room entries (rate ratio (RR) 0.68, p=0.001) and 9.1 fewer minutes of in-room activity (p=0.0002). Also, the length of time between room entrances increased from 26.4 to 45.8 min (p=0.0004). The sleep protocol arm also had lower sound during the rest time block. Mean A-weighted sound was 2.5 decibels lower (p=0.02), and there were 36% fewer peaks (RR 0.64, p=0.02). Light levels were highly variable and not changed by the sleep protocol. Conclusions: Sleep promotion protocols can improve in-room activity and sound. This provides a better sleep opportunity and may, therefore, improve ICU sleep. Trial registration number: 1112009428.

Indexed as

Clinical ProtocolsAcademic Medical CentersAgedAged, 80 and overCritical CareCritical IllnessFemaleHumansIntensive Care UnitsMaleMiddle AgedPilot ProjectsSleepSleep Wake DisordersTertiary Care CentersTreatment Outcomecritical illnessdeliriumintensive care unitlightlux and sleepsound

Identifiers

PMID31258916
PMCPMC6561389

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.