Evidence map›Paper›PMID 31258885›Full record

ReviewJournal of tissue engineering

Eirini A Fragogeorgi, Maritina Rouchota, Maria Georgiou, Marisela Velez, Penelope Bouziotis, George Loudos

Open access · goldAbstract readReview
In one paragraph

Review in Journal of tissue engineering. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Highlights on Advancing Frontiers in Tissue Engineering.Tissue engineering. Part B, Reviews · 2022
    Review
  8. Article
  9. Review
  10. Review
  11. Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Bioactive Glass: Methods for Assessing Angiogenesis and Osteogenesis.Frontiers in cell and developmental biology · 2021
    Review
  17. Human Teeth-Derived Bioceramics for Improved Bone Regeneration.Nanomaterials (Basel, Switzerland) · 2020
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Eirini A FragogeorgiInstitute of Nuclear & Radiological Sciences and Technology, Energy & Safety (INRASTES), NCSR "Demokritos", Athens, Greece.ORCID https://orcid.org/0000-0002-8272-746X
Maritina RouchotaBioemission Technology Solutions (BIOEMTECH), Athens, Greece / Lefkippos Attica Technology Park, NCSR "Demokritos", Athens, Greece.
Maria GeorgiouDepartment of Biomedical Engineering, University of West Attica, Athens, Greece.
Marisela VelezInstituto de Catálisis y Petroleoquímica (CSIC), Madrid, Spain.
Penelope BouziotisInstitute of Nuclear & Radiological Sciences and Technology, Energy & Safety (INRASTES), NCSR "Demokritos", Athens, Greece.
George LoudosInstitute of Nuclear & Radiological Sciences and Technology, Energy & Safety (INRASTES), NCSR "Demokritos", Athens, Greece.
National Centre of Scientific Research "Demokritos" · GRInstituto de Catálisis y Petroleoquímica · ESUniversity of West Attica · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bone is a dynamic tissue that constantly undergoes modeling and remodeling. Bone tissue engineering relying on the development of novel implant scaffolds for the treatment of pre-clinical bone defects has been extensively evaluated by histological techniques. The study of bone remodeling, that takes place over several weeks, is limited by the requirement of a large number of animals and time-consuming and labor-intensive procedures. X-ray-based imaging methods that can non-invasively detect the newly formed bone tissue have therefore been extensively applied in pre-clinical research and in clinical practice. The use of other imaging techniques at a pre-clinical level that act as supportive tools is convenient. This review mainly focuses on nuclear imaging methods (single photon emission computed tomography and positron emission tomography), either alone or used in combination with computed tomography. It addresses their application to small animal models with bone defects, both untreated and filled with substitute materials, to boost the knowledge on bone regenerative processes.

Indexed as

Bone defectshealingsingle photon emission computed tomography/positron emission tomography–computed tomography imagingsubstitute materials

Identifiers

PMID31258885
PMCPMC6589947
OpenAlexW2951014231

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.