Evidence map›Paper›PMID 31258777›Full record

ArticleJournal of Cancer2019

The Diagnostic Value of Serum IGFBP7 in Patients with Esophageal Squamous Cell Carcinoma.

Xinyi Huang, Chaoqun Hong, Yuhui Peng, Shihan Yang, Lisheng Huang, Cantong Liu, Liuyi Chen, Lingyu Chu, Liyan Xu, Yiwei Xu

Open access · goldAbstract read
In one paragraph

Article in Journal of Cancer, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 28 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Xinyi HuangDepartment of Clinical Laboratory Medicine, the Cancer Hospital of Shantou University Medical College, Shantou 515041.
Chaoqun HongDepartment of Oncological Laboratory Research, the Cancer Hospital of Shantou University Medical College, Shantou 515041.
Yuhui PengDepartment of Clinical Laboratory Medicine, the Cancer Hospital of Shantou University Medical College, Shantou 515041.
Shihan YangDepartment of Dermatology and Venereology, Shantou Central Hospital, Shantou 515041.
Lisheng HuangDepartment of Radiation Oncology, the Cancer Hospital of Shantou University Medical College, Shantou 515041.
Cantong LiuDepartment of Clinical Laboratory Medicine, the Cancer Hospital of Shantou University Medical College, Shantou 515041.
Liuyi ChenDepartment of Clinical Laboratory Medicine, the Cancer Hospital of Shantou University Medical College, Shantou 515041.
Lingyu ChuThe Key Laboratory of Molecular Biology for High Cancer Incidence Coastal Chaoshan Area, Shantou University Medical College, Shantou 515041.
Liyan XuThe Key Laboratory of Molecular Biology for High Cancer Incidence Coastal Chaoshan Area, Shantou University Medical College, Shantou 515041.
Yiwei XuDepartment of Clinical Laboratory Medicine, the Cancer Hospital of Shantou University Medical College, Shantou 515041.
Cancer Hospital of Shantou University Medical College · CNShantou University · CNShantou Central Hospital · CNShantou University Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Esophageal squamous cell cancer (ESCC) is one of the leading malignant cancer in the world and especially in China with high incidence and mortality. The exploration of novel serum biomarkers is required for early detection of ESCC. We investigated the diagnostic value of serum insulin like growth factor binding protein 7 (IGFBP7) in ESCC, evaluating its potential to improve the diagnosis of ESCC. The serum samples of 106 patients with ESCC and 107 normal controls were tested by enzyme-linked immunosorbent assay (ELISA). The levels of IGFBP7 in ESCC group were significantly higher than that in normal controls, compared by the Mann-Whitney U test (

Indexed as

biomarkerdiagnosis.esophageal squamous cell carcinomaIGFBP7serum

Identifiers

PMID31258777
PMCPMC6584926
OpenAlexW2951110343

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.