Evidence map›Paper›PMID 31258768›Full record

ReviewJournal of Cancer2019

Biologic Mechanisms Linked to Prognosis in Ovarian Cancer that May Be Affected by Aging.

Hye Sook Chon, Marina Sehovic, Douglas Marchion, Christine Walko, Yin Xiong, Martine Extermann

Open access · goldAbstract readReview
In one paragraph

Review in Journal of Cancer, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Hye Sook ChonDepartment of Gynecology Oncology, Moffitt Cancer Center and Research Institute, Tampa FL, USA.
Marina SehovicSenior Adult Oncology Program, Moffitt Cancer Center and Research Institute, Tampa FL, USA.
Douglas MarchionDepartment of Pathology, Moffitt Cancer Center and Research Institute, Tampa FL, USA.
Christine WalkoDepartment of Individualized Cancer Management, Moffitt Cancer Center and Research Institute, Tampa FL, USA.
Yin XiongDepartment of Pathology, Moffitt Cancer Center and Research Institute, Tampa FL, USA.
Martine ExtermannSenior Adult Oncology Program, Moffitt Cancer Center and Research Institute, Tampa FL, USA.
Moffitt Cancer Center · USUniversity of South Florida · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The increase of both life expectancy of the Western industrialized population and cancer incidence with aging is expected to result in a rapid expansion of the elderly cancer population, including patients with epithelial ovarian cancer (EOC). Although the survival of patients with EOC has generally improved over the past three decades, this progress has yet to provide benefits for elderly patients. Compared with young age, advanced age has been reported as an adverse prognostic factor influencing EOC. However, contradicting results have been obtained, and the mechanisms underlying this observation are poorly defined. Few papers have been published on the underlying biological mechanisms that might explain this prognosis trend. We provide an extensive review of mechanisms that have been linked to EOC prognosis and/or aging in the published literature and might underlie this relationship in humans.

Indexed as

agingbiology of aging and cancerimmunoscenescenceinflammationovarian cancerprognosis

Identifiers

PMID31258768
PMCPMC6584919
OpenAlexW2950565808

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.