ReviewFrontiers in genetics2019
A Review of African Americans' Beliefs and Attitudes About Genomic Studies: Opportunities for Message Design.
Review in Frontiers in genetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
37 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Attitudes and beliefs regarding race-targeted genetic testing of Black people: A systematic review.Journal of genetic counseling · 2023Pooled it
- The relationship between uncertainty and trust in genomic medicine and research: A literature review and thematic analysis.European journal of human genetics : EJHG · 2026Review
- Strategies to build trustworthiness and increase diversity in colorectal cancer biospecimen research: a multi-phase, multi-site qualitative study.Journal of community genetics · 2026Article
- Factors influencing trustworthiness and perceived biases of medical information and genetic testing for Black and White Americans.PLoS genetics · 2025Article
- Acceptability of the ePOWER intervention: Managing previvors' cancer-related uncertainty and supporting decision making.PEC innovation · 2025Article
- Article
- You've got mail: comparing individuals who do and do not provide DNA saliva samples by mail in a study of severe alcohol use disorder.Alcohol and alcoholism (Oxford, Oxfordshire) · 2025Article
- Breaking barriers: fostering equitable access to pediatric genomics through innovative care models and technologies.Pediatric research · 2025Review
- The families SHARE project: novel insights on recruiting and engaging Black men in a community-based genomic education program.BMC public health · 2025Article
- Community Collaboration in Public Health Genetic Literacy: Methods for Co-Designing Educational Resources for Equitable Genomics Research and Practice.Public health genomics · 2025Article
- Key contextual factors involved with participation in medical and genomic screening and research for African American and White Americans: a qualitative inquiry.Journal of community genetics · 2024Article
- Racial Disparities in Genetic Detection Rates for Inherited Retinal Diseases.JAMA ophthalmology · 2024Article
- "I Have Come Because I See You Care About Me": Recruiting Older Black Americans for Genomic Research.Ethnicity & disease · 2024Article
- Using implementation science to evaluate a population-wide genomic screening program: Findings from the first 20,000 In Our DNA SC participants.American journal of human genetics · 2024Article
- Supporting the use of genetic genealogy in restoring family narratives following the transatlantic slave trade.American anthropologist · 2024Article
- Development of a Hereditary Breast and Ovarian Cancer and Genetics Curriculum for Community Health Workers: KEEP IT (Keeping Each other Engaged Program via IT) Community Health Worker Training.Journal of cancer education : the official journal of the American Association for Cancer Education · 2024Article
- Recruiting African American Prostate Cancer Survivors for a Population-based Biobank Study.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2023Article
- Assessing patient-level knowledge of precision medicine in a community health center setting.Journal of community genetics · 2023Article
- The post-diagnostics world: charting a path for pediatric genomic medicine in the twenty-first century.Pediatric research · 2023Article
- Overcoming barriers to informed consent in neurological research: Perspectives from a national survey.Research ethics · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Precision Medicine, the practice of targeting prevention and therapies according to an individual's lifestyle, environment or genetics, holds promise to improve population health outcomes. Within precision medicine, pharmacogenomics (PGX) uses an individual's genome to determine drug response and dosing to tailor therapy. Most PGX studies have been conducted in European populations, but African Americans have greater genetic variation when compared with most populations. Failure to include African Americans in PGX studies may lead to increased health disparities. PGX studies focused on patients of African American descent are needed to identify relevant population specific genetic predictors of drug responses. Recruitment is one barrier to African American participation in PGX. Addressing recruitment challenges is a significant, yet potentially low-cost solution to improve patient accrual and retention. Limited literature exists about African American participation in PGX research, but studies have explored barriers and facilitators among African American participation in genomic studies more broadly. This paper synthesizes the existing literature and extrapolates these findings to PGX studies, with a particular focus on opportunities for message design. Findings from this review can provide guidance for future PGX study recruitment.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.