Evidence map›Paper›PMID 31258541›Full record

ArticleFrontiers in immunology2019

Identification of Autoreactive B Cell Subpopulations in Peripheral Blood of Autoimmune Patients With Pemphigus Vulgaris.

Robert Pollmann, Elias Walter, Thomas Schmidt, Jens Waschke, Michael Hertl, Christian Möbs, Rüdiger Eming

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Review
  5. [Characterization of Immune Reconstitution Patterns in B-cell Subsets Mediated by B-cell Targeted Therapies].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2026
    Article
  6. Article
  7. Article
  8. Review
  9. Engaging T cells for cleanup.Frontiers in immunology · 2025
    Review
  10. Efgartigimod as a novel FcRn inhibitor for autoimmune disease.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024
    Review
  11. Review
  12. Article
  13. Review
  14. Off-Label Uses of Rituximab in Dermatology.Current dermatology reports · 2022
    Review
  15. Article
  16. Review
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Robert PollmannDepartment of Dermatology and Allergology, Philipps-Universität Marburg, Marburg, Germany.
Elias WalterInstitute of Anatomy and Cell Biology, Ludwig-Maximilians-Universität München, Munich, Germany.
Thomas SchmidtDepartment of Dermatology and Allergology, Philipps-Universität Marburg, Marburg, Germany.
Jens WaschkeInstitute of Anatomy and Cell Biology, Ludwig-Maximilians-Universität München, Munich, Germany.
Michael HertlDepartment of Dermatology and Allergology, Philipps-Universität Marburg, Marburg, Germany.
Christian MöbsDepartment of Dermatology and Allergology, Philipps-Universität Marburg, Marburg, Germany.
Rüdiger EmingDepartment of Dermatology and Allergology, Philipps-Universität Marburg, Marburg, Germany.
Philipps University of Marburg · DELudwig-Maximilians-Universität München · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pemphigus vulgaris (PV) is a rare blistering disease caused by IgG autoantibodies against the epidermal adhesion molecules desmoglein (Dsg)3 and Dsg1 providing a well-characterized paradigm of an antibody-mediated organ-specific autoimmune disease. In PV patients who have achieved clinical remission after B cell-depleting therapy, relapses often coincide with a reoccurrence of B cells and Dsg-specific autoantibodies. Here, we analyzed Dsg3-specific B cell subpopulations (i.e., total CD19

Indexed as

AutoantibodiesAutoantigensAutoimmune DiseasesB-LymphocytesB-Lymphocyte SubsetsCells, CulturedDesmoglein 1Desmoglein 3Disease ProgressionEpitopesHumansImmunologic MemoryImmunophenotypingLymphocyte DepletionPemphigusAutoantibodiesAutoantigensDesmoglein 1Desmoglein 3EpitopesautoimmunityB cellsdesmoglein 3flow cytometrypemphigus vulgaris

Identifiers

PMID31258541
PMCPMC6587433
OpenAlexW2949836700

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.