Evidence map›Paper›PMID 31258535›Full record

ArticleFrontiers in immunology2019

Expression and Purification of Hybrid LL-37Tα1 Peptide in

Baseer Ahmad, Quratulain Hanif, Wei Xubiao, Zhang Lulu, Muhammad Shahid, Si Dayong, Zhang Rijun

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 28 citations in OpenAlex.

  1. Review
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  15. Frontiers in bioengineering and biotechnology · 2020
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Baseer AhmadState Key Laboratory of Animal Nutrition and Feed Sciences, College of Animal Science and Technology, China Agricultural University, Beijing, China.
Quratulain HanifState Key Laboratory of Animal Nutrition and Feed Sciences, College of Animal Science and Technology, China Agricultural University, Beijing, China.
Wei XubiaoState Key Laboratory of Animal Nutrition and Feed Sciences, College of Animal Science and Technology, China Agricultural University, Beijing, China.
Zhang LuluState Key Laboratory of Animal Nutrition and Feed Sciences, College of Animal Science and Technology, China Agricultural University, Beijing, China.
Muhammad ShahidState Key Laboratory of Animal Nutrition and Feed Sciences, College of Animal Science and Technology, China Agricultural University, Beijing, China.
Si DayongState Key Laboratory of Animal Nutrition and Feed Sciences, College of Animal Science and Technology, China Agricultural University, Beijing, China.
Zhang RijunState Key Laboratory of Animal Nutrition and Feed Sciences, College of Animal Science and Technology, China Agricultural University, Beijing, China.
China Agricultural University · CNPakistan Institute of Engineering and Applied Sciences · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study pertains to the new approach for the development of hybrid peptide LL-37Tα1 and its biomedical applications. A linear cationic hybrid peptide, LL-37Tα1 was derived from two parental peptides (LL-37 and Tα1) recognized as potent anti-endotoxin without any hemolytic or cytotoxic activity. We successfully cloned the gene of hybrid peptide LL-37Tα1 in PpICZαA vector and expressed in the

Indexed as

PichiaAnimalsAnti-Inflammatory AgentsAntimicrobial Cationic PeptidesCathelicidinsChromatography, High Pressure LiquidCloning, MolecularCytokinesFish ProteinsImmunologic FactorsInflammation MediatorsLipopolysaccharidesL-Lactate DehydrogenaseMiceNitric OxideRAW 264.7 CellsAnti-Inflammatory AgentsAntimicrobial Cationic PeptidesCathelicidinsCytokinesFish ProteinsImmunologic FactorsInflammation MediatorsLipopolysaccharidesL-Lactate DehydrogenaseNitric Oxideapoptosishybrid peptidesimmunomodulatoryLPS neutralizationyeast expression

Identifiers

PMID31258535
PMCPMC6587124
OpenAlexW2949079572

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.