Abnormalities of the Optic Nerve in Down Syndrome and Associations With Visual Acuity.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

1. Prevalence and Etiology of Strabismus in Down Syndrome: A Systematic Review and Meta-Analysis with a Focus on Ethnic Differences in the Esotropia/Exotropia Ratio.Ophthalmic epidemiology · 2025
   Pooled it
2. Prevalence and diversity of retinal disease in adults with Down syndrome.Eye (London, England) · 2025
   Review
3. Classification of congenital cataracts based on multidimensional phenotypes and its association with visual outcomes.International journal of ophthalmology · 2024
   Article
4. RUN(X) out of blood: emerging RUNX1 functions beyond hematopoiesis and links to Down syndrome.Human genomics · 2023
   Review
5. The Ophthalmic Manifestations of Down Syndrome.Children (Basel, Switzerland) · 2023
   Review
6. Single-cell RNA sequencing of neural stem cells derived from human trisomic iPSCs reveals the abnormalities during neural differentiation of Down syndrome.Frontiers in molecular neuroscience · 2023
   Article
7. Widespread kidney anomalies in children with Down syndrome.Pediatric nephrology (Berlin, Germany) · 2022
   Article
8. Neuro-Ophthalmological Manifestations in Children with Down Syndrome: Current Perspectives.Eye and brain · 2021
   Review
9. Down syndrome: a review of ocular manifestations.Therapeutic advances in ophthalmology
   Review

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

Authors and funding

1 author at 1 institution in 1 country.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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