Evidence map›Paper›PMID 31258453›Full record

ArticleDose-response : a publication of International Hormesis Society

Repeated 0.2-Gy γ-Ray Irradiation Attenuates the Inflammatory Process and Endotoxin Damage Induced by Lipopolysaccharides.

Suhe Dong, Wen Qian, Tingting Liu, Hu Liu, Jicong Du, Hainan Zhao, Fu Gao, Jianming Cai

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Dose-response : a publication of International Hormesis Society. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 5 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Suhe DongFaculty of Naval Medicine, Department of Radiation Medicine, Second Military Medical University, Shanghai, China  .
Wen QianFaculty of Naval Medicine, Department of Radiation Medicine, Second Military Medical University, Shanghai, China  .
Tingting LiuFaculty of Naval Medicine, Department of Radiation Medicine, Second Military Medical University, Shanghai, China  .
Hu LiuFaculty of Naval Medicine, Department of Radiation Medicine, Second Military Medical University, Shanghai, China  .
Jicong DuFaculty of Naval Medicine, Department of Radiation Medicine, Second Military Medical University, Shanghai, China  .
Hainan ZhaoFaculty of Naval Medicine, Department of Radiation Medicine, Second Military Medical University, Shanghai, China  .
Fu GaoFaculty of Naval Medicine, Department of Radiation Medicine, Second Military Medical University, Shanghai, China  .
Jianming CaiFaculty of Naval Medicine, Department of Radiation Medicine, Second Military Medical University, Shanghai, China  .
Second Military Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endotoxin damage is an acute, multi-organ disease, the most typical symptoms of which are liver injury and inflammatory cytokine storm. Endotoxin tolerance is described as the pretreatment of lipopolysaccharides (LPS) before the toxin invasion, which is consistent with the adaptive response induced by low-dose radiation (LDR). In this study, we verified that LDR could resist the endotoxin damage by suppressing the increase of inflammatory cytokines, including interleukin 6, tumor necrosis factor, and NO, to improve the survival and relieve the inflammatory cell infiltration, in which low dose of LPS performed consistently with LDR.

Indexed as

adaptive responseendotoxin damagelow-dose radiationLPS

Identifiers

PMID31258453
PMCPMC6590103
OpenAlexW2954234920

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.