Evidence map›Paper›PMID 31258347›Full record

ArticleThe Eurasian journal of medicine2019

Effects of Probiotic Use on Bacterial Translocation in Created Rat Models with Biliary Obstructions.

Mehmet Emin Celikkaya, Bulent Akcora, Sibel Hakverdi, Burcin Ozer, Kemal Turker Ulutas, Nizami Duran

Open access · diamondAbstract read
In one paragraph

Article in The Eurasian journal of medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. The effect ofAnnals of hepato-biliary-pancreatic surgery · 2025
    Article
  2. GutJHEP reports : innovation in hepatology · 2024
    Article
  3. Review
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Mehmet Emin CelikkayaDepartment of Pediatric Surgery, Mustafa Kemal University School of Medicine, Hatay, Turkey.ORCID https://orcid.org/0000-0003-3324-4960
Bulent AkcoraDepartment of Pediatric Surgery, Mustafa Kemal University School of Medicine, Hatay, Turkey.ORCID 0000-0003-3266-2562
Sibel HakverdiDepartment of Pathology, Mustafa Kemal University School of Medicine, Hatay, Turkey.ORCID 0000-0002-1845-6239
Burcin OzerDepartment of Microbiology, Mustafa Kemal University School of Medicine, Hatay, Turkey.ORCID 0000-0001-8965-9335
Kemal Turker UlutasClinic of Biochemistry, Reyhanlı State Hospital, Hatay, Turkey.ORCID https://orcid.org/0000-0003-2852-0449
Nizami DuranDepartment of Microbiology, Mustafa Kemal University School of Medicine, Hatay, Turkey.ORCID 0000-0002-2766-3491
Mustafa Kemal University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe aim of this study was to investigate the protective effects of the combined use of probiotic strains on the development of bacterial translocation in addition to liver and intestinal tissue damage due to biliary obstruction in rats. MATERIALS AND

methodsHere, 3 groups each consisting of 10 rats were created:group 1 (sham group), group 2 (obstructive jaundice), and group 3 (obstructive jaundice+probiotic). Groups 1 and 2 were given 1 cc physiological saline solution by oral gavage twice a day; group 3 was given a probiotic solution that included Lactobacillus acidophilus,

resultsMarkers for liver damage were also found to be significantly improved (p

conclusionOur study showed that the combined use of a probiotic in bile duct obstructions reduced bacterial translocation and alleviated pathological changes arising in the liver and terminal ileum histology.

Indexed as

Bacterial translocationbile duct obstructionscombined use of probiotic microorganismsgram-negative microorganismliver damage

Identifiers

PMID31258347
PMCPMC6592441
OpenAlexW2925362138

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.