ArticleDevelopment and psychopathology2020
Pubertal development mediates the association between family environment and brain structure and function in childhood.
Article in Development and psychopathology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed.
- Weakening of Subcortical and Strengthening of Cortical Visual Pathways Across Early Adolescence.Human brain mapping · 2026Article
- Demographics change the relationships between socioeconomic status, white matter network organization, and cognition in children.Developmental cognitive neuroscience · 2026Article
- Timing and tempo of puberty and neurodevelopment following adversity: A registered report.Developmental cognitive neuroscience · 2026Article
- Does Parental Presence Influence Child Performance on an Emotional Go/No-Go Task at Age 9.5? Exploring the Role of Puberty and Early Environmental Quality.Developmental science · 2026Article
- The Impact of Neighborhood and Family Socioeconomic Status on Adolescents' Internalizing Symptoms: The Mediating Role of Pubertal Development Trajectory.Journal of youth and adolescence · 2025Article
- Adolescent suicide behaviors associate with accelerated reductions in cortical gray matter volume and slower decay of behavioral activation Fun-Seeking scores.Scientific reports · 2025Article
- Negative life events during early adolescence are associated with neural deactivation to emotional stimuli.Brain and cognition · 2025Article
- Characterizing the effects of age, puberty, and sex on variability in resting-state functional connectivity in late childhood and early adolescence.NeuroImage · 2025Article
- Associations between structural stigma and earlier pubertal timing persist for 1 year among Black girls and Latinx youth.Scientific reports · 2025Article
- More similarity than difference: Comparison of within- and between-sex variance in early adolescent brain structure.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- More similarity than difference: comparison of within- and between-sex variance in early adolescent brain structure.Research square · 2024Article
- Article
- Sex, gender diversity, and brain structure in early adolescence.Human brain mapping · 2024Article
- Corticolimbic connectivity mediates the relationship between pubertal timing and mental health problems.Psychological medicine · 2023Article
- Adolescent brain cognitive development study: Longitudinal methods, developmental findings, and associations with environmental risk factors.Developmental cognitive neuroscience · 2023Article
- Childhood trauma, earlier pubertal timing, and psychopathology in adolescence: The role of corticolimbic development.Developmental cognitive neuroscience · 2023Article
- Connecting the dots: social networks in the classroom and white matter connections in the brain.Journal of child psychology and psychiatry, and allied disciplines · 2022Article
- Mediating effect of pubertal stages on the family environment and neurodevelopment: An open-data replication and multiverse analysis of an ABCD StudyNeuroimage. Reports · 2022Article
- Differential Developmental Associations of Material Hardship Exposure and Adolescent Amygdala-Prefrontal Cortex White Matter Connectivity.Journal of cognitive neuroscience · 2022Article
- Does pubertal stage mediate the association between family environment and structure and function of the amygdala-mPFC circuit? A replication study of the longitudinal ABCD cohort.Developmental cognitive neuroscience · 2022Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Psychosocial acceleration theory suggests that pubertal maturation is accelerated in response to adversity. In addition, suboptimal caregiving accelerates development of the amygdala-medial prefrontal cortex circuit. These findings may be related. Here, we assess whether associations between family environment and measures of the amygdala-medial prefrontal cortex circuit are mediated by pubertal development in more than 2000 9- and 10-year-old children from the Adolescent Brain Cognitive Development Study (http://dx.doi.org/10.15154/1412097). Using structural equation modeling, demographic, child-reported, and parent-reported data on family dynamics were compiled into a higher level family environment latent variable. Magnetic resonance imaging preprocessing and compilations were performed by the Adolescent Brain Cognitive Development Study's data analysis core. Anterior cingulate cortex (ACC) thickness, area, white matter fractional anisotropy, amygdala volume, and cingulo-opercular network-amygdala resting-state functional connectivity were assessed. For ACC cortical thickness and ACC fractional anisotropy, significant indirect effects indicated that a stressful family environment relates to more advanced pubertal stage and more mature brain structure. For cingulo-opercular network-amygdala functional connectivity, results indicated a trend in the expected direction. For ACC area, evidence for quadratic mediation by pubertal stage was found. Sex-stratified analyses suggest stronger results for girls. Despite small effect sizes, structural measures of circuits important for emotional behavior are associated with family environment and show initial evidence of accelerated pubertal development.
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