Evidence map›Paper›PMID 31257992›Full record

ArticleMolecular pain

GATA3-dependent epigenetic upregulation of CCL21 is involved in the development of neuropathic pain induced by bortezomib.

Yaochao Zheng, Yang Sun, Yanling Yang, Subo Zhang, Ting Xu, Wenjun Xin, Shaoling Wu, Xiangzhong Zhang

Open access · goldAbstract read
In one paragraph

Article in Molecular pain. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Pathological Mechanisms of Bortezomib-Induced Peripheral Neuropathy.International journal of molecular sciences · 2021
    Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Yaochao Zheng1 Department of Rehabilitation Medicine, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China.
Yang Sun2 Department of Rehabilitation Medicine, The Second Affiliated Hospital of Xi'an Medical University, Xi'an, China.
Yanling Yang3 Department of Hematology, The Third Affiliated Hospital, Sun Yet-Sen University, Guangzhou, China.
Subo Zhang1 Department of Rehabilitation Medicine, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China.
Ting Xu4 Department of Physiology and Pain Research Center, Guangdong Province Key Laboratory of Brain Function and Disease, Zhongshan Medical School, Sun Yat-Sen University, Guangzhou, China.
Wenjun Xin4 Department of Physiology and Pain Research Center, Guangdong Province Key Laboratory of Brain Function and Disease, Zhongshan Medical School, Sun Yat-Sen University, Guangzhou, China.
Shaoling Wu1 Department of Rehabilitation Medicine, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China.ORCID 0000-0001-9761-0662
Xiangzhong Zhang3 Department of Hematology, The Third Affiliated Hospital, Sun Yet-Sen University, Guangzhou, China.
Sun Yat-sen University · CNXi'an Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsBortezomibChemokine CCL21Epigenesis, GeneticGATA3 Transcription FactorImmunohistochemistryImmunoprecipitationMaleMicroarray AnalysisNeuralgiaRats, Sprague-DawleySpinal Cord Dorsal HornBortezomibChemokine CCL21Gata3 protein, ratGATA3 Transcription FactorBortezomibCCL21GATA3neuropathic pain

Identifiers

PMID31257992
PMCPMC6630071
OpenAlexW2953450307

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.