Evidence map›Paper›PMID 31257970›Full record

ArticleJournal of the American Heart Association2019

Associations of Weight Change With Changes in Calf Muscle Characteristics and Functional Decline in Peripheral Artery Disease.

Tamar S Polonsky, Lu Tian, Dongxue Zhang, Lydia A Bazzano, Michael H Criqui, Luigi Ferrucci, Jack M Guralnik, Melina R Kibbe, Christiaan Leeuwenburgh, Robert L Sufit and 1 more

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. How To Assess a Claudication and When To Intervene.Current cardiology reports · 2019
    Review
  5. Article
  6. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 9 institutions in 1 country.

Tamar S Polonsky1 Department of Medicine University of Chicago Chicago IL.
Lu Tian2 Department of Health Research and Policy Stanford University Palo Alto CA.
Dongxue Zhang3 Department of Medicine Northwestern University Feinberg School of Medicine Chicago IL.
Lydia A Bazzano4 Department of Epidemiology Tulane School of Public Health and Tropical Medicine New Orleans LA USA.
Michael H Criqui5 Department of Family Medicine and Public Health University of California at San Diego San Diego CA.
Luigi Ferrucci6 Division of Intramural Research National Institute on Aging Baltimore MD.
Jack M Guralnik7 Department of Epidemiology and Public Health University of Maryland School of Medicine Baltimore MD.
Melina R Kibbe8 Department of Surgery University of North Carolina Chapel Hill NC.
Christiaan Leeuwenburgh9 Department of Aging and Geriatric Research Institute on Aging University of Florida Gainesville FL.
Robert L Sufit3 Department of Medicine Northwestern University Feinberg School of Medicine Chicago IL.
Mary M McDermott3 Department of Medicine Northwestern University Feinberg School of Medicine Chicago IL.
Northwestern University · USNational Institute on Aging · USStanford University · USTulane University · USUniversity of California, San Diego · USUniversity of Chicago · USUniversity of Florida · USUniversity of Maryland, Baltimore · USUniversity of North Carolina at Chapel Hill · US

Funding

Tracking & Evaluation CoreU54GM104940 · NIGMS · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI Leigh Lamonica · 2012 to 2026
$69.1M
University of Florida Older Americans Independence Center (OAIC)P30AG028740 · NIA · UNIVERSITY OF FLORIDA · PI Peihua Qiu · 2007 to 2026
$22.8M
WOMEN'S INTERAGENCY HIV STUDY (WIHS) INTENSIVE PHARMACOKINETICS STUDYM01RR000048 · NCRR · NORTHWESTERN UNIVERSITY AT CHICAGO · PI ARICETA, GEMA · 1985 to 2007
$21.1M
Improving Functioning in Peripheral Arterial DiseaseR01HL073351 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI MCDERMOTT, MARY MCGRAE · 2003 to 2007
$4.9M
BLOOD FACTORS AND PERIPHERAL ARTERIAL DISEASE OUTCOMESR01HL064739 · NHLBI · NORTHWESTERN UNIVERSITY · PI MCDERMOTT, MARY MCGRAE · 2001 to 2004
$2.1M
NCRR NIH HHS M01 RR000048NHLBI NIH HHS R01 HL064739NHLBI NIH HHS R01 HL073351NIA NIH HHS P30 AG028740NIGMS NIH HHS U54 GM104940
6 · The paper itself

Abstract

Background Among people with lower extremity peripheral artery disease, obesity is associated with faster functional decline than normal weight. The association of weight loss with functional decline in peripheral artery disease is unknown. Methods and Results Adults with an ankle-brachial index <0.90 were identified from Chicago-area hospitals in 2002-2004. Weight and 6-minute walk distance were measured annually. Weight change categories were weight loss or gain (≥5 pounds/year at ≥1 visit) or stable (weight change <5 pounds at each visit). Participants reported whether weight loss was "intentional" or "unintentional." Calf muscle area was measured with computed tomography every 2 years. Associations of weight change with changes in calf muscle area and 6-minute walk distance were analyzed using mixed-effects models and adjusted for age, body mass index, ankle-brachial index, physical activity, and other confounders. Among 389 participants, mean ankle-brachial index was 0.63±0.16, mean age was 74.5±7.8, and mean body mass index was 28.1±5.1 kg/m

Indexed as

Walk TestWeight GainWeight LossAgedAged, 80 and overAnkle Brachial IndexFemaleHumansLegMaleMuscle, SkeletalMuscle StrengthObesityOrgan SizeOverweightPeripheral Arterial Diseaseobesityobservational studiesperipheral artery diseasephysical exercise

Identifiers

PMID31257970
PMCPMC6662373
OpenAlexW2954691776

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.