Evidence map›Paper›PMID 31257865›Full record

ArticleBiochemistry2019

The Zebrafish Cytochrome

Matthew B Amdahl, Elin E Petersen, Kaitlin Bocian, Stefan J Kaliszuk, Anthony W DeMartino, Sagarika Tiwari, Courtney E Sparacino-Watkins, Paola Corti, Jason J Rose, Mark T Gladwin and 2 more

Open access · greenAbstract read
In one paragraph

Article in Biochemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

  1. Cytochrome bFree radical biology & medicine · 2026
    Article
  2. CytochromebioRxiv : the preprint server for biology · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

Matthew B AmdahlHeart, Lung, Blood, and Vascular Medicine Institute , University of Pittsburgh , Pittsburgh , Pennsylvania 15261 , United States.
Elin E PetersenDepartment of Bioscience , Aarhus University , DK-8000 Aarhus C, Denmark.
Kaitlin BocianHeart, Lung, Blood, and Vascular Medicine Institute , University of Pittsburgh , Pittsburgh , Pennsylvania 15261 , United States.
Stefan J KaliszukHeart, Lung, Blood, and Vascular Medicine Institute , University of Pittsburgh , Pittsburgh , Pennsylvania 15261 , United States.
Anthony W DeMartinoHeart, Lung, Blood, and Vascular Medicine Institute , University of Pittsburgh , Pittsburgh , Pennsylvania 15261 , United States.
Sagarika TiwariHeart, Lung, Blood, and Vascular Medicine Institute , University of Pittsburgh , Pittsburgh , Pennsylvania 15261 , United States.
Courtney E Sparacino-WatkinsHeart, Lung, Blood, and Vascular Medicine Institute , University of Pittsburgh , Pittsburgh , Pennsylvania 15261 , United States.ORCID 0000-0002-2954-9633
Paola CortiHeart, Lung, Blood, and Vascular Medicine Institute , University of Pittsburgh , Pittsburgh , Pennsylvania 15261 , United States.
Jason J RoseHeart, Lung, Blood, and Vascular Medicine Institute , University of Pittsburgh , Pittsburgh , Pennsylvania 15261 , United States.
Mark T GladwinHeart, Lung, Blood, and Vascular Medicine Institute , University of Pittsburgh , Pittsburgh , Pennsylvania 15261 , United States.
Angela FagoDepartment of Bioscience , Aarhus University , DK-8000 Aarhus C, Denmark.ORCID 0000-0001-7315-2628
Jesús TejeroHeart, Lung, Blood, and Vascular Medicine Institute , University of Pittsburgh , Pittsburgh , Pennsylvania 15261 , United States.ORCID 0000-0003-3245-9978
University of Pittsburgh · USAarhus University · DK

Funding

Vascular Subphenotypes of Lung DiseaseP01HL103455 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI GLADWIN, MARK T · 2011 to 2020
$26.1M
Storage Lesion in Banked Blood Due to Disruption of Nitric Oxide HomeostasisR01HL098032 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Mark T Gladwin · 2009 to 2026
$12.5M
Translational Training Program in Pulmonary Biology and MedicineT32HL007563 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Melanie Koenigshoff · 1985 to 2026
$12.3M
Antidote for inhaled CO poisoning based on mutationally engineered neuroglobinR01HL125886 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Mark T Gladwin, Jesus Tejero Bravo · 2015 to 2026
$7.9M
Cardiovascular Bioengineering Training ProgramT32HL076124 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI SANJEEV G SHROFF · 2005 to 2026
$7.0M
Translational Pulmonary Vascular BiologyT32HL110849 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Sruti Shiva · 2012 to 2026
$5.0M
Discovering and Developing Recombinant Molecular Scavenging Agents for the Treatment of Carbon Monoxide Induced Cardiovascular DysfunctionK08HL136857 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI ROSE, JASON J · 2018 to 2022
$970k
Countermeasure Therapeutics for Acute Lung InjuryR21ES027390 · NIEHS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI LEIKAUF, GEORGE DOUGLAS, TEJERO BRAVO, JESUS · 2016 to 2017
$426k
NHLBI NIH HHS K08 HL136857NHLBI NIH HHS P01 HL103455NHLBI NIH HHS R01 HL098032NHLBI NIH HHS R01 HL125886NHLBI NIH HHS T32 HL007563NHLBI NIH HHS T32 HL076124NHLBI NIH HHS T32 HL110849NIEHS NIH HHS R21 ES027390
6 · The paper itself

Abstract

Cytoglobin is a heme protein evolutionarily related to hemoglobin and myoglobin. Cytoglobin is expressed ubiquitously in mammalian tissues; however, its physiological functions are yet unclear. Phylogenetic analyses indicate that the cytoglobin gene is highly conserved in vertebrate clades, from fish to reptiles, amphibians, birds, and mammals. Most proposed roles for cytoglobin require the maintenance of a pool of reduced cytoglobin (Fe

Indexed as

Biological EvolutionAmino Acid SequenceAnimalsCytochrome-B(5) ReductaseCytochromes b5CytoglobinEnzyme ActivationNADProtein BindingZebrafishCytochrome-B(5) ReductaseCytochromes b5CytoglobinNAD

Identifiers

PMID31257865
PMCPMC6657698
OpenAlexW2954760610

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.