Evidence map›Paper›PMID 31256785›Full record

ReviewNeurologic clinics2019

Genetics of Circadian Rhythms.

Martha Hotz Vitaterna, Kazuhiro Shimomura, Peng Jiang

Open access · greenAbstract readReview
In one paragraph

Review in Neurologic clinics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
0.8field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 35 citations in OpenAlex.

  1. Review
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  3. Article
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  8. Review
  9. Article
  10. Article
  11. Circadian rhythm disruption and endocrine-related tumors.World journal of clinical oncology · 2024
    Review
  12. Article
  13. Biological clock regulation by theFrontiers in cell and developmental biology · 2024
    Review
  14. Article
  15. Review
  16. Review
  17. Article
  18. Review
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Martha Hotz VitaternaCenter for Sleep and Circadian Biology; Department of Neurobiology, Weinberg College of Arts and Sciences, Northwestern University, 2205 Tech Drive, Evanston, IL 60208, USA. Electronic address: m-vitaterna@northwestern.edu.
Kazuhiro ShimomuraCenter for Sleep and Circadian Biology; Davee Department of Neurology, Feinberg School of Medicine, Northwestern University, 420 East Superior Street, Chicago, IL 60611, USA.
Peng JiangCenter for Sleep and Circadian Biology; Department of Neurobiology, Weinberg College of Arts and Sciences, Northwestern University, 2205 Tech Drive, Evanston, IL 60208, USA.
Northwestern University · USCanadian Sleep & Circadian Network · CA

Funding

SLOW WAVE SLEEP AND TYPE 2 DIABETES RISK IN AGINGP01AG011412 · NIA · UNIVERSITY OF CHICAGO · PI ZEE, PHYLLIS C. · 1994 to 2021
$31.5M
NIA NIH HHS P01 AG011412
6 · The paper itself

Abstract

In mammals, genetic influences of circadian rhythms occur at many levels. A set of core "clock genes" have been identified that form a feedback loop of gene transcription and translation. The core genetic clockwork generates circadian rhythms in cells throughout the body. Polymorphisms in both core clock genes and interacting genes contribute to individual differences in the expression and properties of circadian rhythms. The circadian clock profoundly influences the patterns of gene expression and cellular functions, providing a mechanistic basis for the impact of the genetic circadian system on normal physiological processes as well as the development of diseases.

Indexed as

AnimalsCircadian ClocksCircadian RhythmHumansCircadian rhythmsClock genesPatterns of gene activityPolymorphisms

Identifiers

PMID31256785
PMCPMC7202232
OpenAlexW2947961383

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.