Evidence map›Paper›PMID 31256736›Full record

ReviewCritical reviews in toxicology2019

Bisphenol A co-exposure effects: a key factor in understanding BPA's complex mechanism and health outcomes.

Manoj Sonavane, Natalie R Gassman

Abstract readReview
In one paragraph

Review in Critical reviews in toxicology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed.

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  9. Observational
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  12. The influence of endocrine disruptors on the gut microbiota.Turkish journal of medical sciences · 2025
    Review
  13. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Manoj SonavaneDepartment of Oncologic Sciences, University of South Alabama Mitchell Cancer Institute, Mobile, AL, USA.
Natalie R GassmanDepartment of Oncologic Sciences, University of South Alabama Mitchell Cancer Institute, Mobile, AL, USA.ORCID 0000-0002-8488-2332

Funding

Bisphenol A modulation of DNA repair triggered by environmental genotoxic stressR00ES023813 · NIEHS · UNIVERSITY OF SOUTH ALABAMA · PI GASSMAN, NATALIE ROSE · 2016 to 2018
$747k
NIEHS NIH HHS R00 ES023813
6 · The paper itself

Abstract

Bisphenol A (BPA) is an environmental endocrine disrupting chemical widely used in the production of consumer products, such as polycarbonate plastics, epoxies, and thermal receipt paper. Human exposure to BPA is ubiquitous due to its high-volume production and use. BPA exposure has been associated with obesity, diabetes, reproductive disorders, and cancer. Yet, the molecular mechanisms or modes of action underlying these disease outcomes are poorly understood due to the pleiotropic effects induced by BPA. A further confounding factor in understanding BPA's impact on human health is that co-exposure of BPA with endogenous and exogenous agents occurs during the course of daily life. Studies investigating BPA exposure effects and their relationship to adverse health outcomes often ignore interactions between BPA and other chemicals present in the environment. This review examines BPA co-exposure studies to highlight potentially unexplored mechanisms of action and their possible associations with the adverse health effects attributed to BPA. Importantly, both adverse and beneficial co-exposure effects are observed between BPA and natural chemicals or environmental stressors in

Indexed as

Environmental ExposureBenzhydryl CompoundsBisphenol A CompoundsEndocrine DisruptorsEnvironmental PollutantsHumansPhenolsBenzhydryl Compoundsbisphenol ABisphenol A CompoundsEndocrine DisruptorsEnvironmental PollutantsPhenolsadverse effectsanimal modelsBisphenol Acell linesco-exposureenvironmental stressors

Identifiers

PMID31256736
PMCPMC6823117

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.