ArticleJournal of pharmacy practice2020
Fluid Stewardship During Critical Illness: A Call to Action.
Article in Journal of pharmacy practice, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 58 citations in OpenAlex.
- A Data-Driven Medication Regimen Complexity Score for Critically Ill Patients: MRC-ICU 2.0.Pharmacotherapy · 2026Observational
- Appropriateness of intravenous fluid prescriptions in hospitalised patients: a point prevalence study.International journal of clinical pharmacy · 2025Article
- Unsupervised machine learning analysis to identify patterns of ICU medication use for fluid overload prediction.Pharmacotherapy · 2025Article
- Contribution of intravenous medication diluent fluid composition on the development of dyschloremia in intensive care unit patients: A retrospective chart review.SAGE open medicine · 2025Article
- Unsupervised machine learning analysis to identify patterns of ICU medication use for fluid overload prediction.medRxiv : the preprint server for health sciences · 2024Article
- Five sustainable tips about water in the ICU: reduction of water use and decrease of the amount of antibiotics in wastewater.Intensive care medicine · 2024Article
- [Application and control of intravenous fluids in German intensive care units : A national survey among critical care physicians].Die Anaesthesiologie · 2024Article
- Does Point-of-Care Ultrasound Affect Fluid Resuscitation Volume in Patients with Septic Shock: A Retrospective Review.Emergency medicine international · 2024Article
- Aortic thrombosis with visceral malperfusion during circulatory support with a combination of Impella and extracorporeal membrane oxygenation for postcardiotomy cardiogenic shock.Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs · 2023Article
- Machine learning vs. traditional regression analysis for fluid overload prediction in the ICU.Scientific reports · 2023Observational
- Cluster analysis driven by unsupervised latent feature learning of medications to identify novel pharmacophenotypes of critically ill patients.Scientific reports · 2023Article
- Ventilator-associated events: From surveillance to optimizing management.Journal of intensive medicine · 2023Review
- Pharmacophenotype identification of intensive care unit medications using unsupervised cluster analysis of the ICURx common data model.Critical care (London, England) · 2023Observational
- Percent fluid overload for prediction of fluid de-escalation in critically ill patients in Saudi Arabia: a prospective observational study.Acute and critical care · 2023Article
- Pharmacist Metrics in the Pediatric Intensive Care Unit: an Exploration of the Medication Regimen Complexity-Intensive Care Unit (MRC-ICU) Score.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2023Article
- Fluid Stewardship of Maintenance Intravenous Fluids.Journal of pharmacy practice · 2022Review
- Diuretics and the kidney.BJA education · 2022Review
- Hidden Fluids in Plain Sight: Identifying Intravenous Medication Classes as Contributors to Intensive Care Unit Fluid Intake.Hospital pharmacy · 2022Article
- Early Diuretics for De-resuscitation in Septic Patients With Left Ventricular Dysfunction.Clinical Medicine Insights. Cardiology · 2022Article
- Optimization of critical care pharmacy clinical services: A gap analysis approach.American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists · 2021Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Intravenous fluids (IVFs) are the most common drugs administered in the intensive care unit. Despite the ubiquitous use, IVFs are not benign and carry significant risks associated with under- or overadministration. Hypovolemia is associated with decreased organ perfusion, ischemia, and multi-organ failure. Hypervolemia and volume overload are associated with organ dysfunction, delayed liberation from mechanical ventilation, and increased mortality. Despite appropriate provision of IVF, adverse drug effects such as electrolyte abnormalities and acid-base disturbances may occur. The management of volume status in critically ill patients is both dynamic and tenuous, a process that requires frequent monitoring and high clinical acumen. Because patient-specific considerations for fluid therapy evolve across the continuum of critical illness, a standard approach to the assessment of fluid needs and prescription of IVF therapy is necessary. We propose the principle of "fluid stewardship," guided by 4 rights of medication safety: right patient, right drug, right route, and right dose. The successful implementation of fluid stewardship will aid pharmacists in making decisions regarding IVF therapy to optimize hemodynamic management and improve patient outcomes. Additionally, we highlight several areas of focus for future research, guided by the 4 rights construct of fluid stewardship.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.