Evidence map›Paper›PMID 31256326›Full record

ArticleCellular and molecular neurobiology2019

CeO

Jingjing Jia, Changyan Li, Ting Zhang, Jingjing Sun, Sijia Peng, Qizhi Xie, Yining Huang, Li Yi

Open access · greenAbstract read
In one paragraph

Article in Cellular and molecular neurobiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.4field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Biological Applications of Functionalized Cerium Oxide Nanoparticles.International journal of medical sciences · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Jingjing JiaDepartment of Neurology, Peking University First Hospital, No.8 Xishiku Street, Xicheng District, Beijing, 100034, China.
Changyan LiCollege of Chemistry and Chemical Engineering, Inner Mongolia University, Hohhot, Inner Mongolia Province, China.
Ting ZhangDepartment of Phoenix International Medical Center, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, Guangdong Province, China.
Jingjing SunDepartment of Neurology, Peking University Shenzhen Hospital, Shenzhen, 518036, Guangdong Province, China.
Sijia PengDepartment of Neurology, Peking University Shenzhen Hospital, Shenzhen, 518036, Guangdong Province, China.
Qizhi XieDepartment of Neurology, Peking University Shenzhen Hospital, Shenzhen, 518036, Guangdong Province, China.
Yining HuangDepartment of Neurology, Peking University First Hospital, No.8 Xishiku Street, Xicheng District, Beijing, 100034, China. ynhuang@bjmu.edu.cn.
Li YiDepartment of Neurology, Peking University Shenzhen Hospital, Shenzhen, 518036, Guangdong Province, China. yilitj@hotmail.com.
Peking University Shenzhen Hospital · CNPeking University First Hospital · CNFifth Affiliated Hospital of Sun Yat-sen University · CNInner Mongolia University · CN

Funding

Basic Research Project of Peking University Shenzhen Hospital JCYJ2018012Beijing Key Laboratory BZ0250Health and Family Planning Commission of Shenzhen Municipality Fund SZSM201812096Inner Mongolia Education Department Key Project NJZZ16015Inner Mongolia University Startup Fund Project 21300-5145152The Inner Mongolia Natural Science Foundation 2016MS0216
6 · The paper itself

Abstract

Microglia are the inherent immune effector cells in the central nervous system (CNS), are activated rapidly when the CNS is stimulated by ischaemia, infection, injury, etc. and participate in and aggravate the development of inflammatory reactions in the CNS. During the process of microglial activation, inflammatory factors such as TNF-α and IL-1β and an abundance of reactive oxygen species (ROS)/reactive nitrogen species (RNS), are released by damaged nerve cells. LXW7 is a small molecule peptide and specifically binds with integrin αvβ3. Cerium oxide nanoparticles (nanoceria) are strong free radical scavengers and are widely used in many studies. In this research, a model of inflammation was established using lipopolysaccharide (LPS) to induce BV2 microglia activation, and the effects of CeO

Indexed as

Acrylic ResinsAnimalsCell LineCell SurvivalCeriumFocal Adhesion Protein-Tyrosine KinasesInflammationIntegrin alphaVbeta3Interleukin-1betaLipopolysaccharidesMiceMicrogliaModels, BiologicalNanoparticlesNitric OxideNitric Oxide Synthase Type IIAcrylic Resinscarbopol 940ceric oxideCeriumFocal Adhesion Protein-Tyrosine KinasesIntegrin alphaVbeta3Interleukin-1betaLipopolysaccharidesNitric OxideNitric Oxide Synthase Type IIPeptidesReactive Oxygen SpeciesRNA, MessengerSTAT3 Transcription FactorTumor Necrosis Factor-alphaCerium nanoparticlesInflammationIntegrin αvβ3LXW7Oxidative stress

Identifiers

PMID31256326
PMCPMC11452219
OpenAlexW2956140210

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.