Evidence map›Paper›PMID 31256281›Full record

ArticleJournal of neurology2019

Prospective memory in Parkinson's disease: the role of the motor subtypes.

Alfonsina D'Iorio, Gianpaolo Maggi, Carmine Vitale, Marianna Amboni, Diana Di Meglio, Luigi Trojano, Gabriella Santangelo

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Journal of neurology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Longitudinal changes in prospective memory in patients with Parkinson's disease.Journal of neural transmission (Vienna, Austria : 1996) · 2026
    Article
  3. Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Alfonsina D'IorioDepartment of Psychology, University of Campania "Luigi Vanvitelli", Caserta, Italy.
Gianpaolo MaggiDepartment of Psychology, University of Campania "Luigi Vanvitelli", Caserta, Italy.
Carmine VitaleDepartment of Motor Sciences and Wellness, University "Parthenope", Naples, Italy.
Marianna AmboniInstitute of Diagnosis and Health, IDC-Hermitage Capodimonte, Naples, Italy.
Diana Di MeglioDepartment of Psychology, University of Campania "Luigi Vanvitelli", Caserta, Italy.
Luigi TrojanoDepartment of Psychology, University of Campania "Luigi Vanvitelli", Caserta, Italy.
Gabriella SantangeloDepartment of Psychology, University of Campania "Luigi Vanvitelli", Caserta, Italy. gabriella.santangelo@unicampania.it.ORCID http://orcid.org/0000-0002-7728-852X
University of Campania "Luigi Vanvitelli" · ITParthenope University of Naples · ITUniversity of Salerno · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundProspective memory (PM) is defined as memory for future intentions and it is typically divided into time-based and event-based PM. Deficit of PM has been reported in patients with Parkinson's disease (PD) but no study has yet explored the association between motor subtypes (tremor dominant and rigidity/bradykinesia dominant) and performance on PM tasks. The aim of the study was to explore the role of motor subtypes in the defect of PM.

methodsConsecutive outpatients with tremor dominant (TD-PD) or rigidity/bradykinesia dominant (PIGD-PD) PD and healthy subjects (HCs) were enrolled and underwent a neuropsychological battery assessing PM, verbal memory and executive functions and questionnaires assessing apathy, functional autonomy, and perceived memory disturbances.

resultsWe enrolled 28 patients with TD-PD, 28 patients with PIGD-PD and 50 HCs. The three groups did not differ on demographic and cognitive variables. Patients with TD-PD performed worse on time-based PM tasks than patients with PIGD-PD and HCs; no significant difference was found among the three groups on event-based PM tasks. Executive dysfunctions contributed to reduced time-based PM scores in TD-PD. Moreover, severe deficit of time-based and more frequency of perceived failures of PM contributed to reduced functional autonomy in TD-PD.

conclusionThe finding of a poorer performance of patients with TD-PD than ones with PIGD-PD and HCs suggests a selective deficit of time-based PM abilities in TD-PD group; therefore, deficit of time-based PM might be considered as a distinctive non-motor symptom of TD-PD and it might affect the functional autonomy in this subtype of PD.

Indexed as

Memory, EpisodicAgedCognitive DysfunctionExecutive FunctionFemaleHumansHypokinesiaMaleMiddle AgedMuscle RigidityParkinson DiseaseTremorCognitive dysfunctionsParkinson’s diseasePostural instability/gait difficulty subtypeProspective memoryTremor dominant subtype

Identifiers

PMID31256281
OpenAlexW2954520076

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.